Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise
Although physical exercise strongly influences several laboratory parameters, data about the hematological changes after medium distance running are scarce. We studied 31 middle-trained athletes (mean training regimen 217±32 min/week) who performed a 21.1 km, half-marathon run. Blood samples were co...
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2014/192173 |
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doaj-0ef230af6a1a4ce681978579b30f993e2021-07-02T09:05:42ZengHindawi LimitedAdvances in Hematology1687-91041687-91122014-01-01201410.1155/2014/192173192173Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance ExerciseGiuseppe Lippi0Gian Luca Salvagno1Elisa Danese2Cantor Tarperi3Gian Cesare Guidi4Federico Schena5Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Via Gramsci 14, 43126 Parma, ItalyLaboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona, Via delle Menegone, 37100 Verona, ItalyLaboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona, Via delle Menegone, 37100 Verona, ItalyDepartment of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Via delle Menegone, 37100 Verona, ItalyLaboratory of Clinical Biochemistry, Department of Life and Reproduction Sciences, University of Verona, Via delle Menegone, 37100 Verona, ItalyDepartment of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Via delle Menegone, 37100 Verona, ItalyAlthough physical exercise strongly influences several laboratory parameters, data about the hematological changes after medium distance running are scarce. We studied 31 middle-trained athletes (mean training regimen 217±32 min/week) who performed a 21.1 km, half-marathon run. Blood samples were collected before the run, at the end, and 3 and 20 hours thereafter. The complete blood count was performed on Advia 2120 and included red blood cell (RBC), reticulocyte, and platelet counts; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); reticulocyte haemoglobin content (Ret CHR); RBC distribution width (RDW), mean platelet volume (MPV). No significant variations were observed for MCH and Ret CHR. The RBC, reticulocyte, and hemoglobin values modestly decreased after the run. The MCV significantly increased at the end of running but returned to baseline 3 hours thereafter. The RDW constantly increased, reaching a peak 20 hours after the run. The platelet count and MPV both increased after the run and returned to baseline 3 hours thereafter. These results may have implications for definition of reference ranges and antidoping testing, and may also contribute to explaining the relationship between endurance exercise and mortality, since previous studies reported that RDW and MPV may be significantly associated with cardiovascular disease.http://dx.doi.org/10.1155/2014/192173 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Giuseppe Lippi Gian Luca Salvagno Elisa Danese Cantor Tarperi Gian Cesare Guidi Federico Schena |
spellingShingle |
Giuseppe Lippi Gian Luca Salvagno Elisa Danese Cantor Tarperi Gian Cesare Guidi Federico Schena Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise Advances in Hematology |
author_facet |
Giuseppe Lippi Gian Luca Salvagno Elisa Danese Cantor Tarperi Gian Cesare Guidi Federico Schena |
author_sort |
Giuseppe Lippi |
title |
Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise |
title_short |
Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise |
title_full |
Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise |
title_fullStr |
Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise |
title_full_unstemmed |
Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise |
title_sort |
variation of red blood cell distribution width and mean platelet volume after moderate endurance exercise |
publisher |
Hindawi Limited |
series |
Advances in Hematology |
issn |
1687-9104 1687-9112 |
publishDate |
2014-01-01 |
description |
Although physical exercise strongly influences several laboratory parameters, data about the hematological changes after medium distance running are scarce. We studied 31 middle-trained athletes (mean training regimen 217±32 min/week) who performed a 21.1 km, half-marathon run. Blood samples were collected before the run, at the end, and 3 and 20 hours thereafter. The complete blood count was performed on Advia 2120 and included red blood cell (RBC), reticulocyte, and platelet counts; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); reticulocyte haemoglobin content (Ret CHR); RBC distribution width (RDW), mean platelet volume (MPV). No significant variations were observed for MCH and Ret CHR. The RBC, reticulocyte, and hemoglobin values modestly decreased after the run. The MCV significantly increased at the end of running but returned to baseline 3 hours thereafter. The RDW constantly increased, reaching a peak 20 hours after the run. The platelet count and MPV both increased after the run and returned to baseline 3 hours thereafter. These results may have implications for definition of reference ranges and antidoping testing, and may also contribute to explaining the relationship between endurance exercise and mortality, since previous studies reported that RDW and MPV may be significantly associated with cardiovascular disease. |
url |
http://dx.doi.org/10.1155/2014/192173 |
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