Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation
BackgroundNo new therapies for traumatic brain injury (TBI) have been officially translated into current practice. At the tissue and cellular level, both inflammatory and oxidative processes may be exacerbated post-injury and contribute to further brain damage. N-acetylcysteine (NAC) has the potenti...
Main Authors: | Junaid Bhatti, Barto Nascimento, Umbreen Akhtar, Shawn G. Rhind, Homer Tien, Avery Nathens, Luis Teodoro da Luz |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-01-01
|
Series: | Frontiers in Neurology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fneur.2017.00744/full |
Similar Items
-
Prevention and reversal of selenite-induced cataracts by N-acetylcysteine amide in Wistar rats
by: Yasaswi Maddirala, et al.
Published: (2017-04-01) -
Medical and Dietary Uses of N-Acetylcysteine
by: Špela Šalamon, et al.
Published: (2019-04-01) -
Protective Effect of N-Acetylcysteine Amide on Blast-Induced Increase in Intracranial Pressure in Rats
by: Usmah Kawoos, et al.
Published: (2017-06-01) -
N-acetylcysteine Amide Ameliorates Blast-Induced Changes in Blood-Brain Barrier Integrity in Rats
by: Usmah Kawoos, et al.
Published: (2019-06-01) -
N-Acetylcysteine Provides Analgesic Effect in Rats
by: Yasaman Amini, et al.
Published: (2013-12-01)