Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation
Endothelial cell function and metabolism are closely linked to differential use of energy substrate sources and combustion. While endothelial cell migration is promoted by 2‐phosphofructokinase‐6/fructose‐2,6‐bisphosphatase (PFKFB3)‐driven glycolysis, proliferation also depends on fatty acid oxidati...
Main Authors: | Jonas Aakre Wik, Danh Phung, Shrikant Kolan, Guttorm Haraldsen, Bjørn Steen Skålhegg, Johanna Hol Fosse |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-06-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.13174 |
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