Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway

Certain caspase-8 null cell lines demonstrate resistance to Fas-induced apoptosis, indicating that the Fas/FasL apoptotic pathway may be caspase-8-dependent. Some reports, however, have shown that Fas induces cell death independent of caspase-8. Here we provide evidence for an alternative, caspase-8...

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Bibliographic Details
Main Authors: Hanping Feng, Yi Zeng, Michael W. Graner, Luke Whitesell, Emmanuel Katsanis
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/S1110724304308041

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