Evidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic Pathway
Certain caspase-8 null cell lines demonstrate resistance to Fas-induced apoptosis, indicating that the Fas/FasL apoptotic pathway may be caspase-8-dependent. Some reports, however, have shown that Fas induces cell death independent of caspase-8. Here we provide evidence for an alternative, caspase-8...
Main Authors: | Hanping Feng, Yi Zeng, Michael W. Graner, Luke Whitesell, Emmanuel Katsanis |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2004-01-01
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Series: | Journal of Biomedicine and Biotechnology |
Online Access: | http://dx.doi.org/10.1155/S1110724304308041 |
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