Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity

Tyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary...

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Main Authors:	Natalia I. Moguillansky, MD, Hafiz Abdul Moiz Fakih, MD, John R. Wingard, MD
Format:	Article
Language:	English
Published:	Elsevier 2017-01-01
Series:	Respiratory Medicine Case Reports
Subjects:	Bosutinib Tyrosine kinase inhibitors Pleural effusions Pulmonary arterial hypertension Interstitial lung disease
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213007117300552

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spelling	doaj-0f20e877fe8c4be8bd61549a4168cd1e2020-11-24T23:22:17ZengElsevierRespiratory Medicine Case Reports2213-00712017-01-0121C15415710.1016/j.rmcr.2017.05.003Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicityNatalia I. Moguillansky, MD0Hafiz Abdul Moiz Fakih, MD1John R. Wingard, MD2University of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USAUniversity of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USAUniversity of Florida, UF Health Bone Marrow Transplant – Shands Hospital, 1515 SW Archer Rd, Suite #100, Gainesville, FL 32608, USATyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary toxicities, including pulmonary hypertension and interstitial lung disease.http://www.sciencedirect.com/science/article/pii/S2213007117300552BosutinibTyrosine kinase inhibitorsPleural effusionsPulmonary arterial hypertensionInterstitial lung disease
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD
spellingShingle	Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity Respiratory Medicine Case Reports Bosutinib Tyrosine kinase inhibitors Pleural effusions Pulmonary arterial hypertension Interstitial lung disease
author_facet	Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD
author_sort	Natalia I. Moguillansky, MD
title	Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
title_short	Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
title_full	Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
title_fullStr	Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
title_full_unstemmed	Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
title_sort	bosutinib induced pleural effusions: case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
publisher	Elsevier
series	Respiratory Medicine Case Reports
issn	2213-0071
publishDate	2017-01-01
description	Tyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary toxicities, including pulmonary hypertension and interstitial lung disease.
topic	Bosutinib Tyrosine kinase inhibitors Pleural effusions Pulmonary arterial hypertension Interstitial lung disease
url	http://www.sciencedirect.com/science/article/pii/S2213007117300552
work_keys_str_mv	AT nataliaimoguillanskymd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity AT hafizabdulmoizfakihmd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity AT johnrwingardmd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity
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Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity

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