| Summary: | Italian ryegrass is a major weed problem in wheat (<i>Triticum aestivum</i> L.) production worldwide. Two separate studies were conducted in Stoneville, Mississippi to evaluate: (1) the efficacy of herbicides available to Mississippi producers for controlling glyphosate-resistant (GR) Italian ryegrass (control study), and (2) fall burndown herbicide seed suppression study. Results of the control study showed that flufenacet/metribuzin EPOST followed by (fb) pinoxaden LPOST (standard treatment) provided 93% control of GR Italian ryegrass. Some other treatments provided comparable Italian ryegrass control (92% to 97%) as the standard treatment in 2017. Italian ryegrass control in the seed suppression study was 100%, 100%, 67.5%, 97%, and 99.5% from the application of the following treatments: (1) <i>S</i>-metolachlor + flumioxazin + paraquat in October−November fb glyphosate + clethodim in January−February fb gramoxone as needed (weed-free check); (2) <i>S</i>-metolachlor + flumioxazin + paraquat in October−November; (3) field cultivator (disk) in October−November; (4) glyphosate + clethodim in January−February; and (5) field cultivator in October−November fb glyphosate + clethodim in January−February, respectively. The remaining Italian ryegrass from the application of treatments 3, 4, and 5 produced 65,700; 1008; and 9 seeds m<sup>−2</sup>, respectively. Seed suppression study highlights the importance of 100% control that is required to manage GR Italian grass.
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