A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report

A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report

Abstract Background An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. Case presentation We report the case of a 29-year-old human immunodefic...

Full description

Bibliographic Details
Main Authors: Xue Chen, Lin Jia, Yongfeng Wu, Jing Chang, Tong Zhang, Yingmin Ma, Yulin Zhang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Infectious Diseases
Subjects:
Talaromyces marneffei
HIV
AIDS
Upper abdominal mass
Next-generation sequencing
Online Access:https://doi.org/10.1186/s12879-021-06489-7
Description
Summary:Abstract Background An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. Case presentation We report the case of a 29-year-old human immunodeficiency virus (HIV) infected man who presented with an upper abdominal mass and without any symptoms related with infection. Histopathology and next-generation sequencing (NGS) following biopsy of the mass confirmed T. marneffei-infected lymphadenopathy, and the patient was successfully treated with amphotericin B and itraconazole. Conclusions This case report suggests that potential fungal infection should be considered during the diagnostic workup of a mass in clinical practice.
ISSN:1471-2334

Similar Items