OPN –Revisited
Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cel...
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doaj-0f65e64bce554a4caa77129ab86e31572020-11-25T02:37:15ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196ZE10ZE1310.7860/JCDR/2015/12872.6111OPN –RevisitedVijayanirmala Subraman0Muthukumar Thiyagarajan1N.Malathi2Sharada T. Rajan3Senior Lecturer, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Associate Professor, Department of Anatomy, Sri Ramachandra University, Porur, Chennai, India.Professor and Head, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Reader, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cell adhesion, migration and cell survival, angiogenesis, apoptosis, inflammation and wound healing. This review summarizes the current data of the biological activities of OPN in the development of tumour, its progression and metastasis. https://jcdr.net/articles/PDF/6111/12872_CE[Ra]_F(P)_PF1(ANAK)_PFA(AK)_PF2(PAG).pdfangiogenesiscell adhesionmetastasisosteopontin |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Vijayanirmala Subraman Muthukumar Thiyagarajan N.Malathi Sharada T. Rajan |
spellingShingle |
Vijayanirmala Subraman Muthukumar Thiyagarajan N.Malathi Sharada T. Rajan OPN –Revisited Journal of Clinical and Diagnostic Research angiogenesis cell adhesion metastasis osteopontin |
author_facet |
Vijayanirmala Subraman Muthukumar Thiyagarajan N.Malathi Sharada T. Rajan |
author_sort |
Vijayanirmala Subraman |
title |
OPN –Revisited |
title_short |
OPN –Revisited |
title_full |
OPN –Revisited |
title_fullStr |
OPN –Revisited |
title_full_unstemmed |
OPN –Revisited |
title_sort |
opn –revisited |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2015-06-01 |
description |
Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney,
bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and
pathologic events such as cell adhesion, migration and cell survival, angiogenesis, apoptosis, inflammation and wound healing. This
review summarizes the current data of the biological activities of OPN in the development of tumour, its progression and metastasis. |
topic |
angiogenesis cell adhesion metastasis osteopontin |
url |
https://jcdr.net/articles/PDF/6111/12872_CE[Ra]_F(P)_PF1(ANAK)_PFA(AK)_PF2(PAG).pdf |
work_keys_str_mv |
AT vijayanirmalasubraman opnrevisited AT muthukumarthiyagarajan opnrevisited AT nmalathi opnrevisited AT sharadatrajan opnrevisited |
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1724795882188046336 |