OPN –Revisited

Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cel...

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Main Authors: Vijayanirmala Subraman, Muthukumar Thiyagarajan, N.Malathi, Sharada T. Rajan
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6111/12872_CE[Ra]_F(P)_PF1(ANAK)_PFA(AK)_PF2(PAG).pdf
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spelling doaj-0f65e64bce554a4caa77129ab86e31572020-11-25T02:37:15ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-06-0196ZE10ZE1310.7860/JCDR/2015/12872.6111OPN –RevisitedVijayanirmala Subraman0Muthukumar Thiyagarajan1N.Malathi2Sharada T. Rajan3Senior Lecturer, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Associate Professor, Department of Anatomy, Sri Ramachandra University, Porur, Chennai, India.Professor and Head, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Reader, Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Porur, Chennai, India.Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cell adhesion, migration and cell survival, angiogenesis, apoptosis, inflammation and wound healing. This review summarizes the current data of the biological activities of OPN in the development of tumour, its progression and metastasis. https://jcdr.net/articles/PDF/6111/12872_CE[Ra]_F(P)_PF1(ANAK)_PFA(AK)_PF2(PAG).pdfangiogenesiscell adhesionmetastasisosteopontin
collection DOAJ
language English
format Article
sources DOAJ
author Vijayanirmala Subraman
Muthukumar Thiyagarajan
N.Malathi
Sharada T. Rajan
spellingShingle Vijayanirmala Subraman
Muthukumar Thiyagarajan
N.Malathi
Sharada T. Rajan
OPN –Revisited
Journal of Clinical and Diagnostic Research
angiogenesis
cell adhesion
metastasis
osteopontin
author_facet Vijayanirmala Subraman
Muthukumar Thiyagarajan
N.Malathi
Sharada T. Rajan
author_sort Vijayanirmala Subraman
title OPN –Revisited
title_short OPN –Revisited
title_full OPN –Revisited
title_fullStr OPN –Revisited
title_full_unstemmed OPN –Revisited
title_sort opn –revisited
publisher JCDR Research and Publications Private Limited
series Journal of Clinical and Diagnostic Research
issn 2249-782X
0973-709X
publishDate 2015-06-01
description Osteopontin (OPN), a matrix extracellular glyco-phosphoprotein is found in various tissues such as epithelium lined tissues, kidney, bone and teeth .It is also detected in all body fluids including blood and breast milk. OPN plays role in a number of physiological and pathologic events such as cell adhesion, migration and cell survival, angiogenesis, apoptosis, inflammation and wound healing. This review summarizes the current data of the biological activities of OPN in the development of tumour, its progression and metastasis.
topic angiogenesis
cell adhesion
metastasis
osteopontin
url https://jcdr.net/articles/PDF/6111/12872_CE[Ra]_F(P)_PF1(ANAK)_PFA(AK)_PF2(PAG).pdf
work_keys_str_mv AT vijayanirmalasubraman opnrevisited
AT muthukumarthiyagarajan opnrevisited
AT nmalathi opnrevisited
AT sharadatrajan opnrevisited
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