Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment
Background. Early bone loss due to tooth extraction can be significantly reduced by socket preservation. The aim of this study was to compare the in vivo effects of hemihydrate calcium sulfate granules (an alloplastic material) and Cerabone (a bovine-derived xenograft) on socket preservation in dogs...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2018-12-01
|
Series: | Journal of Dental Research, Dental Clinics, Dental Prospects |
Subjects: | |
Online Access: | https://joddd.tbzmed.ac.ir/PDF/joddd-21070 |
id |
doaj-0f6b67f6e9004c2fb6d988342d9f303a |
---|---|
record_format |
Article |
spelling |
doaj-0f6b67f6e9004c2fb6d988342d9f303a2020-11-25T00:29:08ZengTabriz University of Medical SciencesJournal of Dental Research, Dental Clinics, Dental Prospects2008-210X2008-21182018-12-0112423824410.15171/joddd.2018.037joddd-21070Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experimentNaser Sargolzaie0Mehrnaz Rafiee1Hamideh Salari Sedigh2Reza Zare Mahmoudabadi3Hooman Keshavarz4Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, IranPeriodontist, Mashhad, IranDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran3Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, IranDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Community Oral Health, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranBackground. Early bone loss due to tooth extraction can be significantly reduced by socket preservation. The aim of this study was to compare the in vivo effects of hemihydrate calcium sulfate granules (an alloplastic material) and Cerabone (a bovine-derived xenograft) on socket preservation in dogs. Methods. Six male Mongrel dogs were randomly divided into 2 groups (n=3) for sacrificing and histological evaluation 4 and 8 weeks after a surgery. The second and third premolars on both sides of the lower jaw were extracted surgically. The sockets on one side were filled with Cerabone, and with calcium sulfate on the opposite side. In the slides, the ratio of the area of newly formed bone to the area of the entire cavity, and the ratio of the area of fibrous connective tissue to the area of the entire cavity were measured. The presence of inflammation was also examined. Wilcoxon signed-rank test, Sign test and McNemar test were used for statistical analyses (ɑ=0.05). Results. The means of new bone proportion were 11% and 8% for Cerabone and calcium sulfate, respectively (P=0.58). The means of connective tissue proportion were 29% and 33% for Cerabone and calcium sulfate, respectively (P=0.72). No inflammatory cells were observed in the Cerabone group, although 50% of the samples in the calcium sulfate group showed inflammation (P=0.50). Conclusion. The effects of calcium sulfate and Cerabone on socket preservation in dogs on bone formation, fibrous connective tissue and inflammation levels were not significantly different at 4- and 8-week postoperative intervals.https://joddd.tbzmed.ac.ir/PDF/joddd-21070Animal experimentcalcium sulfateCerabonedogsocket preservation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Naser Sargolzaie Mehrnaz Rafiee Hamideh Salari Sedigh Reza Zare Mahmoudabadi Hooman Keshavarz |
spellingShingle |
Naser Sargolzaie Mehrnaz Rafiee Hamideh Salari Sedigh Reza Zare Mahmoudabadi Hooman Keshavarz Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment Journal of Dental Research, Dental Clinics, Dental Prospects Animal experiment calcium sulfate Cerabone dog socket preservation |
author_facet |
Naser Sargolzaie Mehrnaz Rafiee Hamideh Salari Sedigh Reza Zare Mahmoudabadi Hooman Keshavarz |
author_sort |
Naser Sargolzaie |
title |
Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment |
title_short |
Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment |
title_full |
Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment |
title_fullStr |
Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment |
title_full_unstemmed |
Comparison of the effect of hemihydrate calcium sulfate granules and Cerabone on dental socket preservation: An animal experiment |
title_sort |
comparison of the effect of hemihydrate calcium sulfate granules and cerabone on dental socket preservation: an animal experiment |
publisher |
Tabriz University of Medical Sciences |
series |
Journal of Dental Research, Dental Clinics, Dental Prospects |
issn |
2008-210X 2008-2118 |
publishDate |
2018-12-01 |
description |
Background. Early bone loss due to tooth extraction can be significantly reduced by socket preservation. The aim of this study was to compare the in vivo effects of hemihydrate calcium sulfate granules (an alloplastic material) and Cerabone (a bovine-derived xenograft) on socket preservation in dogs. Methods. Six male Mongrel dogs were randomly divided into 2 groups (n=3) for sacrificing and histological evaluation 4 and 8 weeks after a surgery. The second and third premolars on both sides of the lower jaw were extracted surgically. The sockets on one side were filled with Cerabone, and with calcium sulfate on the opposite side. In the slides, the ratio of the area of newly formed bone to the area of the entire cavity, and the ratio of the area of fibrous connective tissue to the area of the entire cavity were measured. The presence of inflammation was also examined. Wilcoxon signed-rank test, Sign test and McNemar test were used for statistical analyses (ɑ=0.05). Results. The means of new bone proportion were 11% and 8% for Cerabone and calcium sulfate, respectively (P=0.58). The means of connective tissue proportion were 29% and 33% for Cerabone and calcium sulfate, respectively (P=0.72). No inflammatory cells were observed in the Cerabone group, although 50% of the samples in the calcium sulfate group showed inflammation (P=0.50). Conclusion. The effects of calcium sulfate and Cerabone on socket preservation in dogs on bone formation, fibrous connective tissue and inflammation levels were not significantly different at 4- and 8-week postoperative intervals. |
topic |
Animal experiment calcium sulfate Cerabone dog socket preservation |
url |
https://joddd.tbzmed.ac.ir/PDF/joddd-21070 |
work_keys_str_mv |
AT nasersargolzaie comparisonoftheeffectofhemihydratecalciumsulfategranulesandceraboneondentalsocketpreservationananimalexperiment AT mehrnazrafiee comparisonoftheeffectofhemihydratecalciumsulfategranulesandceraboneondentalsocketpreservationananimalexperiment AT hamidehsalarisedigh comparisonoftheeffectofhemihydratecalciumsulfategranulesandceraboneondentalsocketpreservationananimalexperiment AT rezazaremahmoudabadi comparisonoftheeffectofhemihydratecalciumsulfategranulesandceraboneondentalsocketpreservationananimalexperiment AT hoomankeshavarz comparisonoftheeffectofhemihydratecalciumsulfategranulesandceraboneondentalsocketpreservationananimalexperiment |
_version_ |
1725333137048731648 |