ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition
ATP-dependent chromatin remodeling factors of the SNF2 family are key components of the cellular machineries that shape and regulate chromatin structure and function. Members of this group of proteins have broad and heterogeneous functions ranging from controlling gene activity, facilitating DNA dam...
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2011-10-01
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Online Access: | http://www.mdpi.com/1422-0067/12/10/6544/ |
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doaj-0f9991874ad5415e8d2d52e62bbf11762020-11-25T00:56:06ZengMDPI AGInternational Journal of Molecular Sciences1422-00672011-10-0112106544656510.3390/ijms12106544ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber CompositionAlexandra LusserAnette ZeilnerPaolo PiattiATP-dependent chromatin remodeling factors of the SNF2 family are key components of the cellular machineries that shape and regulate chromatin structure and function. Members of this group of proteins have broad and heterogeneous functions ranging from controlling gene activity, facilitating DNA damage repair, promoting homologous recombination to maintaining genomic stability. Several chromatin remodeling factors are critical components of nucleosome assembly processes, and recent reports have identified specific functions of distinct chromatin remodeling factors in the assembly of variant histones into chromatin. In this review we will discuss the specific roles of ATP-dependent chromatin remodeling factors in determining nucleosome composition and, thus, chromatin fiber properties.http://www.mdpi.com/1422-0067/12/10/6544/chromatinhistone variantchromatin remodeling factorcentromerelinker histonechromatin assembly |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alexandra Lusser Anette Zeilner Paolo Piatti |
spellingShingle |
Alexandra Lusser Anette Zeilner Paolo Piatti ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition International Journal of Molecular Sciences chromatin histone variant chromatin remodeling factor centromere linker histone chromatin assembly |
author_facet |
Alexandra Lusser Anette Zeilner Paolo Piatti |
author_sort |
Alexandra Lusser |
title |
ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition |
title_short |
ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition |
title_full |
ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition |
title_fullStr |
ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition |
title_full_unstemmed |
ATP-Dependent Chromatin Remodeling Factors and Their Roles in Affecting Nucleosome Fiber Composition |
title_sort |
atp-dependent chromatin remodeling factors and their roles in affecting nucleosome fiber composition |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2011-10-01 |
description |
ATP-dependent chromatin remodeling factors of the SNF2 family are key components of the cellular machineries that shape and regulate chromatin structure and function. Members of this group of proteins have broad and heterogeneous functions ranging from controlling gene activity, facilitating DNA damage repair, promoting homologous recombination to maintaining genomic stability. Several chromatin remodeling factors are critical components of nucleosome assembly processes, and recent reports have identified specific functions of distinct chromatin remodeling factors in the assembly of variant histones into chromatin. In this review we will discuss the specific roles of ATP-dependent chromatin remodeling factors in determining nucleosome composition and, thus, chromatin fiber properties. |
topic |
chromatin histone variant chromatin remodeling factor centromere linker histone chromatin assembly |
url |
http://www.mdpi.com/1422-0067/12/10/6544/ |
work_keys_str_mv |
AT alexandralusser atpdependentchromatinremodelingfactorsandtheirrolesinaffectingnucleosomefibercomposition AT anettezeilner atpdependentchromatinremodelingfactorsandtheirrolesinaffectingnucleosomefibercomposition AT paolopiatti atpdependentchromatinremodelingfactorsandtheirrolesinaffectingnucleosomefibercomposition |
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