Primary Angle Closure and Sequence Variants within MicroRNA Binding Sites of Genes Involved in Eye Development.

The formation of primary angle closure (PAC) and primary angle closure glaucoma (PACG) is regulated by a tissue remodeling pathway that plays a critical role in eye development. MicroRNAs (miRNAs) are powerful gene expression regulators and may exert their effects on tissue remodeling genes. This st...

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Bibliographic Details
Main Authors: Haihong Shi, Junfang Zhang, Rongrong Zhu, Nan Hu, Hong Lu, Mei Yang, Bai Qin, Jian Shi, Huaijin Guan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5100968?pdf=render