Computational Insight into the Effect of Natural Compounds on the Destabilization of Preformed Amyloid-β(1–40) Fibrils

One of the principal hallmarks of Alzheimer’s disease (AD) is related to the aggregation of amyloid-β fibrils in an insoluble form in the brain, also known as amyloidosis. Therefore, a prominent therapeutic strategy against AD consists of either blocking the amyloid aggregation an...

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Bibliographic Details
Main Authors: Francesco Tavanti, Alfonso Pedone, Maria Cristina Menziani
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/6/1320

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