Biochemical characterization of recombinant Avihepatovirus 3C protease and its localization

Biochemical characterization of recombinant Avihepatovirus 3C protease and its localization

Abstract Background The picornaviral 3C protease mediates viral polyprotein maturation and multiple cleavages of host proteins to modulate viral translation and transcription. The 3C protease has been regarded as a valid target due to its structural similarity among different picornaviruses and mini...

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Bibliographic Details
Main Authors: Di Sun, Mingshu Wang, Xingjian Wen, Sai Mao, Anchun Cheng, Renyong Jia, Qiao Yang, Ying Wu, Dekang Zhu, Shun Chen, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Xiaoyue Chen, Yunya Liu, Yanling Yu, Ling Zhang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Virology Journal
Subjects:
DHAV
3C protease
Protease activity
Localization
Online Access:http://link.springer.com/article/10.1186/s12985-019-1155-3

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