Does applicability domain exist in microarray-based genomic research?
Constructing an accurate predictive model for clinical decision-making on the basis of a relatively small number of tumor samples with high-dimensional microarray data remains a very challenging problem. The validity of such models has been seriously questioned due to their failure in clinical valid...
Main Authors: | Li Shao, Leihong Wu, Hong Fang, Weida Tong, Xiaohui Fan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2883551?pdf=render |
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