A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.
Oligodendroglioma poses a biological conundrum for malignant adult human gliomas: it is a tumor type that is universally incurable for patients, and yet, only a few of the human tumors have been established as cell populations in vitro or as intracranial xenografts in vivo. Their survival, thus, may...
Main Authors: | Barbara Klink, Hrvoje Miletic, Daniel Stieber, Peter C Huszthy, Jaime Alberto Campos Valenzuela, Jörg Balss, Jian Wang, Manja Schubert, Per Øystein Sakariassen, Terje Sundstrøm, Anja Torsvik, Mads Aarhus, Rupavathana Mahesparan, Andreas von Deimling, Lars Kaderali, Simone P Niclou, Evelin Schröck, Rolf Bjerkvig, Janice M Nigro |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23527265/pdf/?tool=EBI |
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