Inactivation of FOXA2 by Respiratory Bacterial Pathogens and Dysregulation of Pulmonary Mucus Homeostasis

Inactivation of FOXA2 by Respiratory Bacterial Pathogens and Dysregulation of Pulmonary Mucus Homeostasis

Forkhead box (FOX) proteins are transcriptional factors that regulate various cellular processes. This minireview provides an overview of FOXA2 functions, with a special emphasis on the regulation airway mucus homeostasis in both healthy and diseased lungs. FOXA2 plays crucial roles during lung morp...

Full description

Bibliographic Details
Main Authors: Woosuk Choi, Shawn Choe, Gee W. Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
chronic lung diseases
mucus homeostasis
mucociliary clearance
FOXA2
EGFR
STAT6
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00515/full

Similar Items

Similar Items