Cell-based glycan arrays for probing glycan–glycan binding protein interactions
Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-03245-5 |
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Article |
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doaj-0ffb5181213f47b5a814ffdccd1b37952021-05-11T10:01:33ZengNature Publishing GroupNature Communications2041-17232018-02-019111110.1038/s41467-018-03245-5Cell-based glycan arrays for probing glycan–glycan binding protein interactionsJennie Grace Briard0Hao Jiang1Kelley W. Moremen2Matthew Scott Macauley3Peng Wu4Department of Molecular Medicine, The Scripps Research InstituteKey Laboratory of Marine Drugs, Ministry of Education and Qingdao National Laboratory for Marine Science & Technology and Shandong Provincial Key Laboratory of Glycoscience & Glycoengineering, School of Medicine and Pharmacy, Ocean University of ChinaComplex Carbohydrate Research Center and the Department of Biochemistry and Molecular Biology, University of GeorgiaDepartment of Molecular Medicine, The Scripps Research InstituteDepartment of Molecular Medicine, The Scripps Research InstituteGlycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags.https://doi.org/10.1038/s41467-018-03245-5 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu |
| spellingShingle |
Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu Cell-based glycan arrays for probing glycan–glycan binding protein interactions Nature Communications |
| author_facet |
Jennie Grace Briard Hao Jiang Kelley W. Moremen Matthew Scott Macauley Peng Wu |
| author_sort |
Jennie Grace Briard |
| title |
Cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| title_short |
Cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| title_full |
Cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| title_fullStr |
Cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| title_full_unstemmed |
Cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| title_sort |
cell-based glycan arrays for probing glycan–glycan binding protein interactions |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-02-01 |
| description |
Glycans, interaction platforms protruding from the surface of cells, are hard to study due to their diverse architecture. Here, the authors present a method to obtain cells carrying defined glycans, which can then be used to find proteins specifically recognizing these tags. |
| url |
https://doi.org/10.1038/s41467-018-03245-5 |
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1721448794960166912 |