Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4

Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4

Aims: Dietary supplementation with ursolic acid (UA) prevents monocyte dysfunction in diabetic mice and protects mice against atherosclerosis and loss of renal function. The goal of this study was to determine the molecular mechanism by which UA prevents monocyte dysfunction induced by metabolic st...

Full description

Bibliographic Details
Main Authors: Sarah L. Ullevig, Hong Seok Kim, Huynh Nga Nguyen, William S. Hambright, Andrew J. Robles, Sina Tavakoli, Reto Asmis
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Ursolic acid
Nox4
Monocyte
S-glutathionylation
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000184

Similar Items

Similar Items