The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso)
Dengue is an emerging infectious disease of global significance. Although this virus has been reported for a long time, its significance within the burden of diseases in West Africa is not obvious, especially in Burkina Faso. Our objective was to evaluate flavivirus presence in Ouagadougou (Burkina...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-12-01
|
Series: | International Journal of Environmental Research and Public Health |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-4601/13/12/1226 |
id |
doaj-101463bd0c954084bae1516be12933cf |
---|---|
record_format |
Article |
spelling |
doaj-101463bd0c954084bae1516be12933cf2020-11-24T23:50:53ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012016-12-011312122610.3390/ijerph13121226ijerph13121226The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso)Florence Fournet0Stéphane Rican1Zoé Vaillant2Anna Roudot3Aude Meunier-Nikiema4Daouda Kassié5Roch K. Dabiré6Gérard Salem7Unité Mixte de Recherche Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle (MIVEGEC), Institut de Recherche pour le Développement, Montpellier 34394, FranceLaboratoire Dynamiques Sociales et Recomposition des Espaces (LADYSS), Université Paris Ouest Nanterre La Défense, Nanterre 92000, FranceLaboratoire Dynamiques Sociales et Recomposition des Espaces (LADYSS), Université Paris Ouest Nanterre La Défense, Nanterre 92000, FranceLaboratoire Dynamiques Sociales et Recomposition des Espaces (LADYSS), Université Paris Ouest Nanterre La Défense, Nanterre 92000, FranceInstitut des Sciences des Sociétés, Ouagadougou BP 7047, Burkina FasoLaboratoire Dynamiques Sociales et Recomposition des Espaces (LADYSS), Université Paris Ouest Nanterre La Défense, Nanterre 92000, FranceInstitut de Recherche en Sciences de la Santé/Centre Muraz, Bobo-Dioulasso BP 545, Burkina FasoLaboratoire Dynamiques Sociales et Recomposition des Espaces (LADYSS), Université Paris Ouest Nanterre La Défense, Nanterre 92000, FranceDengue is an emerging infectious disease of global significance. Although this virus has been reported for a long time, its significance within the burden of diseases in West Africa is not obvious, especially in Burkina Faso. Our objective was to evaluate flavivirus presence in Ouagadougou (Burkina Faso) and the link between anti-flavivirus antibody seroprevalence and urbanization modes. A population-based cross-sectional survey was conducted and 3015 children were enrolled from Ouagadougou districts with different types and degrees of urbanization (with/without equipment and high/low building density). Flavivirus (FLAV) IgM MAC-ELISA and FLAV indirect IgG ELISA were performed. Associations between FLAV IgG presence (sign of past infection) and various independent variables were assessed using the chi-square test and a multivariate logistic regression analysis. The apparent prevalence of past flavivirus infections among the enrolled children was 22.7% (95% CI: 22.4–26.7) (n = 685). Eleven children (0.4%; 95% CI: 0.61–2.14) were positive for FLAV IgM, indicating active transmission. Factors associated with flavivirus infection were identified among the enrolled children (age, sex), householders (educational level, asset index) and in the environment (building density, water access, waste management and house appearance); however, they showed great variability according to the city districts. The water access modality did not significantly influence FLAV IgG positivity. Conversely, apparently good practices of waste management had unexpected consequences (increased risk related to municipal dumpsters). Given the scale of ongoing urbanization and the spread of arboviral diseases, close collaboration between health and city stakeholders is needed.http://www.mdpi.com/1660-4601/13/12/1226West AfricaBurkina Fasourban healthhealth inequalitiesinfectious diseasesarboviruses |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Florence Fournet Stéphane Rican Zoé Vaillant Anna Roudot Aude Meunier-Nikiema Daouda Kassié Roch K. Dabiré Gérard Salem |
spellingShingle |
Florence Fournet Stéphane Rican Zoé Vaillant Anna Roudot Aude Meunier-Nikiema Daouda Kassié Roch K. Dabiré Gérard Salem The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) International Journal of Environmental Research and Public Health West Africa Burkina Faso urban health health inequalities infectious diseases arboviruses |
author_facet |
Florence Fournet Stéphane Rican Zoé Vaillant Anna Roudot Aude Meunier-Nikiema Daouda Kassié Roch K. Dabiré Gérard Salem |
author_sort |
Florence Fournet |
title |
The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) |
title_short |
The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) |
title_full |
The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) |
title_fullStr |
The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) |
title_full_unstemmed |
The Influence of Urbanization Modes on the Spatial Circulation of Flaviviruses within Ouagadougou (Burkina Faso) |
title_sort |
influence of urbanization modes on the spatial circulation of flaviviruses within ouagadougou (burkina faso) |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1660-4601 |
publishDate |
2016-12-01 |
description |
Dengue is an emerging infectious disease of global significance. Although this virus has been reported for a long time, its significance within the burden of diseases in West Africa is not obvious, especially in Burkina Faso. Our objective was to evaluate flavivirus presence in Ouagadougou (Burkina Faso) and the link between anti-flavivirus antibody seroprevalence and urbanization modes. A population-based cross-sectional survey was conducted and 3015 children were enrolled from Ouagadougou districts with different types and degrees of urbanization (with/without equipment and high/low building density). Flavivirus (FLAV) IgM MAC-ELISA and FLAV indirect IgG ELISA were performed. Associations between FLAV IgG presence (sign of past infection) and various independent variables were assessed using the chi-square test and a multivariate logistic regression analysis. The apparent prevalence of past flavivirus infections among the enrolled children was 22.7% (95% CI: 22.4–26.7) (n = 685). Eleven children (0.4%; 95% CI: 0.61–2.14) were positive for FLAV IgM, indicating active transmission. Factors associated with flavivirus infection were identified among the enrolled children (age, sex), householders (educational level, asset index) and in the environment (building density, water access, waste management and house appearance); however, they showed great variability according to the city districts. The water access modality did not significantly influence FLAV IgG positivity. Conversely, apparently good practices of waste management had unexpected consequences (increased risk related to municipal dumpsters). Given the scale of ongoing urbanization and the spread of arboviral diseases, close collaboration between health and city stakeholders is needed. |
topic |
West Africa Burkina Faso urban health health inequalities infectious diseases arboviruses |
url |
http://www.mdpi.com/1660-4601/13/12/1226 |
work_keys_str_mv |
AT florencefournet theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT stephanerican theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT zoevaillant theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT annaroudot theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT audemeuniernikiema theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT daoudakassie theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT rochkdabire theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT gerardsalem theinfluenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT florencefournet influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT stephanerican influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT zoevaillant influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT annaroudot influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT audemeuniernikiema influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT daoudakassie influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT rochkdabire influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso AT gerardsalem influenceofurbanizationmodesonthespatialcirculationofflaviviruseswithinouagadougouburkinafaso |
_version_ |
1725478472422260736 |