Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus

Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus

Abstract Background Zika virus (ZIKV) infection is a global health problem, and its complications, including congenital Zika syndrome and Guillain-Barré syndrome, constitute a continued threat to humans. Unfortunately, effective therapeutics against ZIKV infection are not available thus far. Methods...

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Bibliographic Details
Main Authors: Jie Yuan, Jianchen Yu, Yun Huang, Zhenjian He, Jia Luo, Yun Wu, Yingchun Zheng, Jueheng Wu, Xun Zhu, Haihe Wang, Mengfeng Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Medicine
Subjects:
Zika virus
Fidaxomicin
RdRp inhibitor
NS5
Antiviral
Online Access:http://link.springer.com/article/10.1186/s12916-020-01663-1

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