The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study
Abstract Background Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest...
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2020-01-01
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Series: | BMC Geriatrics |
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Online Access: | https://doi.org/10.1186/s12877-020-1423-5 |
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Article |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Werayuth Srithumsuk Mai Kabayama Yasuyuki Gondo Yukie Masui Yuya Akagi Nonglak Klinpudtan Eri Kiyoshige Kayo Godai Ken Sugimoto Hiroshi Akasaka Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Madoka Ogawa Hiroki Inagaki Tatsuro Ishizaki Yasumichi Arai Hiromi Rakugi Kei Kamide |
spellingShingle |
Werayuth Srithumsuk Mai Kabayama Yasuyuki Gondo Yukie Masui Yuya Akagi Nonglak Klinpudtan Eri Kiyoshige Kayo Godai Ken Sugimoto Hiroshi Akasaka Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Madoka Ogawa Hiroki Inagaki Tatsuro Ishizaki Yasumichi Arai Hiromi Rakugi Kei Kamide The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study BMC Geriatrics Stroke Cognitive decline Older and oldest people |
author_facet |
Werayuth Srithumsuk Mai Kabayama Yasuyuki Gondo Yukie Masui Yuya Akagi Nonglak Klinpudtan Eri Kiyoshige Kayo Godai Ken Sugimoto Hiroshi Akasaka Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Madoka Ogawa Hiroki Inagaki Tatsuro Ishizaki Yasumichi Arai Hiromi Rakugi Kei Kamide |
author_sort |
Werayuth Srithumsuk |
title |
The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study |
title_short |
The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study |
title_full |
The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study |
title_fullStr |
The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study |
title_full_unstemmed |
The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study |
title_sort |
importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the sonic study |
publisher |
BMC |
series |
BMC Geriatrics |
issn |
1471-2318 |
publishDate |
2020-01-01 |
description |
Abstract Background Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study was to investigate the importance of stroke as a risk factor of cognitive decline during 3 years in community dwelling older and oldest people. Methods This study was longitudinal study with a 3-year follow-up in Japan. The participants were 1333 community dwelling older and oldest people (70 years old = 675, 80 years old = 589, and 90 years old = 69). Data collected included basic data (age, sex, and history of stroke), vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and current smoking), and social factors (educational level, frequency of going outdoors, long-term care (LTC) service used, and residential area). The Japanese version of the Montreal Cognitive Assessment (MoCA-J) was decline of ≥2 points was defined as cognitive decline. Multiple logistic regression analysis was used to investigate the association between stroke and other risk factors with cognitive decline during a 3-year follow-up. Results The fit of the hypothesized model by multiple logistic regression showed that a history of stroke, advanced age, and greater MoCA-J score at the baseline were important risk factors, while the presence of dyslipidemia and a higher educational level were protective factors that were significantly correlated with cognitive decline during the 3-year follow-up. Conclusions The cognitive decline after the 3-year follow-up was influenced by the history of stroke and advanced age, while greater MoCA-J score at the baseline was positively associated with subsequent 3 years cognitive decline. The protective factors were the presence of dyslipidemia and a higher educational level. Therefore, these factors are considered important and should be taken into consideration when searching for creative solutions to prevent cognitive decline after stroke in community dwelling older and oldest people. |
topic |
Stroke Cognitive decline Older and oldest people |
url |
https://doi.org/10.1186/s12877-020-1423-5 |
work_keys_str_mv |
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doaj-104f45ec8f4548d2a3a3c2894a57cc2d2021-01-24T12:10:15ZengBMCBMC Geriatrics1471-23182020-01-0120111010.1186/s12877-020-1423-5The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC studyWerayuth Srithumsuk0Mai Kabayama1Yasuyuki Gondo2Yukie Masui3Yuya Akagi4Nonglak Klinpudtan5Eri Kiyoshige6Kayo Godai7Ken Sugimoto8Hiroshi Akasaka9Yoichi Takami10Yasushi Takeya11Koichi Yamamoto12Kazunori Ikebe13Madoka Ogawa14Hiroki Inagaki15Tatsuro Ishizaki16Yasumichi Arai17Hiromi Rakugi18Kei Kamide19Department of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Clinical Thanatology and Geriatric Behavioral Science, Graduate School of Human Sciences, Osaka UniversityTokyo Metropolitan Geriatric Hospital and Institute of GerontologyDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Prosthodontics, Gerodontology and Oral Rehabilitation, Graduate School of Dentistry, Osaka UniversityTokyo Metropolitan Geriatric Hospital and Institute of GerontologyTokyo Metropolitan Geriatric Hospital and Institute of GerontologyTokyo Metropolitan Geriatric Hospital and Institute of GerontologyCenter for Supercentenarian Medical Research, Keio University School of MedicineDepartment of Geriatric and General Medicine, Graduate School of Medicine, Osaka UniversityDepartment of Health Promotion System Sciences, Division of Health Sciences, Graduate School of Medicine, Osaka UniversityAbstract Background Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study was to investigate the importance of stroke as a risk factor of cognitive decline during 3 years in community dwelling older and oldest people. Methods This study was longitudinal study with a 3-year follow-up in Japan. The participants were 1333 community dwelling older and oldest people (70 years old = 675, 80 years old = 589, and 90 years old = 69). Data collected included basic data (age, sex, and history of stroke), vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and current smoking), and social factors (educational level, frequency of going outdoors, long-term care (LTC) service used, and residential area). The Japanese version of the Montreal Cognitive Assessment (MoCA-J) was decline of ≥2 points was defined as cognitive decline. Multiple logistic regression analysis was used to investigate the association between stroke and other risk factors with cognitive decline during a 3-year follow-up. Results The fit of the hypothesized model by multiple logistic regression showed that a history of stroke, advanced age, and greater MoCA-J score at the baseline were important risk factors, while the presence of dyslipidemia and a higher educational level were protective factors that were significantly correlated with cognitive decline during the 3-year follow-up. Conclusions The cognitive decline after the 3-year follow-up was influenced by the history of stroke and advanced age, while greater MoCA-J score at the baseline was positively associated with subsequent 3 years cognitive decline. The protective factors were the presence of dyslipidemia and a higher educational level. Therefore, these factors are considered important and should be taken into consideration when searching for creative solutions to prevent cognitive decline after stroke in community dwelling older and oldest people.https://doi.org/10.1186/s12877-020-1423-5StrokeCognitive declineOlder and oldest people |