Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma

Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma

Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western countries. It encompasses a spectrum of conditions ranging from simple steatosis to more severe and progressive non-alcoholic steatohepatitis (NASH) that can lead to hepatocellular carcinoma (H...

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Bibliographic Details
Main Authors: Sophie Jacques, Arash Arjomand, Hélène Perée, Patrick Collins, Alice Mayer, Arnaud Lavergne, Marie Wéry, Myriam Mni, Alexandre Hego, Virginie Thuillier, Guillaume Becker, Mohamed Ali Bahri, Alain Plenevaux, Emmanuel Di Valentin, Cécile Oury, Michel Moutschen, Philippe Delvenne, Nicolas Paquot, Souad Rahmouni
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85089-6

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