TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells

While non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells, which protects against pathogenic bacteria.

Bibliographic Details
Main Authors:	Eun A. Ra, Taeyun A. Lee, Seung Won Kim, Areum Park, Hyun jin Choi, Insook Jang, Sujin Kang, Jae Hee Cheon, Jin Won Cho, Ji Eun Lee, Sungwook Lee, Boyoun Park
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms11726

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spelling	doaj-105465ca7a7148d1ab2b63fadbbbcb8b2021-05-11T10:37:12ZengNature Publishing GroupNature Communications2041-17232016-05-017111510.1038/ncomms11726TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cellsEun A. Ra0Taeyun A. Lee1Seung Won Kim2Areum Park3Hyun jin Choi4Insook Jang5Sujin Kang6Jae Hee Cheon7Jin Won Cho8Ji Eun Lee9Sungwook Lee10Boyoun Park11Department of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Internal Medicine and Institute of Gastroenterology, Yonsei University College of MedicineDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Integrated OMICS for Biomedical Science, Yonsei UniversityDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Internal Medicine and Institute of Gastroenterology, Yonsei University College of MedicineDepartment of Integrated OMICS for Biomedical Science, Yonsei UniversityDepartment of Health Science and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan UniversityDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei UniversityWhile non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells, which protects against pathogenic bacteria.https://doi.org/10.1038/ncomms11726
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Eun A. Ra Taeyun A. Lee Seung Won Kim Areum Park Hyun jin Choi Insook Jang Sujin Kang Jae Hee Cheon Jin Won Cho Ji Eun Lee Sungwook Lee Boyoun Park
spellingShingle	Eun A. Ra Taeyun A. Lee Seung Won Kim Areum Park Hyun jin Choi Insook Jang Sujin Kang Jae Hee Cheon Jin Won Cho Ji Eun Lee Sungwook Lee Boyoun Park TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells Nature Communications
author_facet	Eun A. Ra Taeyun A. Lee Seung Won Kim Areum Park Hyun jin Choi Insook Jang Sujin Kang Jae Hee Cheon Jin Won Cho Ji Eun Lee Sungwook Lee Boyoun Park
author_sort	Eun A. Ra
title	TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
title_short	TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
title_full	TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
title_fullStr	TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
title_full_unstemmed	TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells
title_sort	trim31 promotes atg5/atg7-independent autophagy in intestinal cells
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-05-01
description	While non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells, which protects against pathogenic bacteria.
url	https://doi.org/10.1038/ncomms11726
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TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells

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