A pragmatic evidence-based approach to post-mortem perinatal imaging
Abstract Post-mortem imaging has a high acceptance rate amongst parents and healthcare professionals as a non-invasive method for investigating perinatal deaths. Previously viewed as a ‘niche’ subspecialty, it is becoming increasingly requested, with general radiologists now more frequently asked to...
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doaj-1098ba03a4b94e09b57924a21e669d4b2021-07-18T11:10:58ZengSpringerOpenInsights into Imaging1869-41012021-07-0112111110.1186/s13244-021-01042-1A pragmatic evidence-based approach to post-mortem perinatal imagingSusan C. Shelmerdine0J. Ciaran Hutchinson1Celine Lewis2Ian C. Simcock3Thivya Sekar4Neil J. Sebire5Owen J. Arthurs6Great Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street Hospital for Children NHS Foundation TrustPopulation, Policy and Practice Department, UCL GOS Institute of Child HealthGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street Hospital for Children NHS Foundation TrustGreat Ormond Street Hospital for Children NHS Foundation TrustAbstract Post-mortem imaging has a high acceptance rate amongst parents and healthcare professionals as a non-invasive method for investigating perinatal deaths. Previously viewed as a ‘niche’ subspecialty, it is becoming increasingly requested, with general radiologists now more frequently asked to oversee and advise on appropriate imaging protocols. Much of the current literature to date has focussed on diagnostic accuracy and clinical experiences of individual centres and their imaging techniques (e.g. post-mortem CT, MRI, ultrasound and micro-CT), and pragmatic, evidence-based guidance for how to approach such referrals in real-world practice is lacking. In this review, we summarise the latest research and provide an approach and flowchart to aid decision-making for perinatal post-mortem imaging. We highlight key aspects of the maternal and antenatal history that radiologists should consider when protocolling studies (e.g. antenatal imaging findings and history), and emphasise important factors that could impact the diagnostic quality of post-mortem imaging examinations (e.g. post-mortem weight and time interval). Considerations regarding when ancillary post-mortem image-guided biopsy tests are beneficial are also addressed, and we provide key references for imaging protocols for a variety of cross-sectional imaging modalities.https://doi.org/10.1186/s13244-021-01042-1RadiologyAutopsyDiagnostic imagingFoetusPregnancy loss |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Susan C. Shelmerdine J. Ciaran Hutchinson Celine Lewis Ian C. Simcock Thivya Sekar Neil J. Sebire Owen J. Arthurs |
spellingShingle |
Susan C. Shelmerdine J. Ciaran Hutchinson Celine Lewis Ian C. Simcock Thivya Sekar Neil J. Sebire Owen J. Arthurs A pragmatic evidence-based approach to post-mortem perinatal imaging Insights into Imaging Radiology Autopsy Diagnostic imaging Foetus Pregnancy loss |
author_facet |
Susan C. Shelmerdine J. Ciaran Hutchinson Celine Lewis Ian C. Simcock Thivya Sekar Neil J. Sebire Owen J. Arthurs |
author_sort |
Susan C. Shelmerdine |
title |
A pragmatic evidence-based approach to post-mortem perinatal imaging |
title_short |
A pragmatic evidence-based approach to post-mortem perinatal imaging |
title_full |
A pragmatic evidence-based approach to post-mortem perinatal imaging |
title_fullStr |
A pragmatic evidence-based approach to post-mortem perinatal imaging |
title_full_unstemmed |
A pragmatic evidence-based approach to post-mortem perinatal imaging |
title_sort |
pragmatic evidence-based approach to post-mortem perinatal imaging |
publisher |
SpringerOpen |
series |
Insights into Imaging |
issn |
1869-4101 |
publishDate |
2021-07-01 |
description |
Abstract Post-mortem imaging has a high acceptance rate amongst parents and healthcare professionals as a non-invasive method for investigating perinatal deaths. Previously viewed as a ‘niche’ subspecialty, it is becoming increasingly requested, with general radiologists now more frequently asked to oversee and advise on appropriate imaging protocols. Much of the current literature to date has focussed on diagnostic accuracy and clinical experiences of individual centres and their imaging techniques (e.g. post-mortem CT, MRI, ultrasound and micro-CT), and pragmatic, evidence-based guidance for how to approach such referrals in real-world practice is lacking. In this review, we summarise the latest research and provide an approach and flowchart to aid decision-making for perinatal post-mortem imaging. We highlight key aspects of the maternal and antenatal history that radiologists should consider when protocolling studies (e.g. antenatal imaging findings and history), and emphasise important factors that could impact the diagnostic quality of post-mortem imaging examinations (e.g. post-mortem weight and time interval). Considerations regarding when ancillary post-mortem image-guided biopsy tests are beneficial are also addressed, and we provide key references for imaging protocols for a variety of cross-sectional imaging modalities. |
topic |
Radiology Autopsy Diagnostic imaging Foetus Pregnancy loss |
url |
https://doi.org/10.1186/s13244-021-01042-1 |
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