Long Non-Coding RNA CCAT2 Promotes the Development of Esophageal Squamous Cell Carcinoma by Inhibiting miR-200b to Upregulate the IGF2BP2/TK1 Axis

Long Non-Coding RNA CCAT2 Promotes the Development of Esophageal Squamous Cell Carcinoma by Inhibiting miR-200b to Upregulate the IGF2BP2/TK1 Axis

Long non-coding RNAs (lncRNAs) have been shown to play important roles in human cancers, including esophageal squamous cell carcinoma (ESCC). In the current study, we identified CCAT2 as a relevant lncRNA and investigated its role in the progression of ESCC. RT-qPCR was adopted to detect CCAT2 expre...

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Bibliographic Details
Main Authors: Xiaodan Wu, Yihui Fan, Yupeng Liu, Biao Shen, Haimin Lu, Haitao Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
long non-coding RNA CCAT2
microRNA-200b
insulin-like growth factor 2 mRNA-binding protein 2
competing endogenous RNA
thymidine kinase 1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.680642/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.680642/full

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