Evaluation of the cardiotoxicity of mitragynine and its analogues using human induced pluripotent stem cell-derived cardiomyocytes.
INTRODUCTION:Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant with opioid-like effects for the treatment of...
Main Authors: | Jun Lu, Heming Wei, Jianjun Wu, Mohd Fadzly Amar Jamil, Mei Lan Tan, Mohd Ilham Adenan, Philip Wong, Winston Shim |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4275233?pdf=render |
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