| Summary: | <i>Background and objectives:</i> Numerous theoretical and clinical advances have been made through research on person-centered care (PCC). Nevertheless, care is still focused on the medical aspects of treating patients’ diseases in Korea, and thus providing individualized PCC to patients tends to be neglected. This study aimed to investigate the relationship between PCC competence, empathic competence, interpersonal competence, and perceived stress to identify the factors that impact PCC competence for developing programs that foster PCC competence in nursing students. <i>Materials and Methods:</i><i> </i>Data were collected from 149 participants, which comprised third- and fourth-year nursing students from two universities in Korea who have experienced clinical training. PCC competence, empathic competence, interpersonal competence, and perceived stress were measured using structured self-reported questionnaires. <i>Results</i>: PCC competence was positively correlated with empathic competence (<i>p</i> < 0.001) and interpersonal competence (<i>p</i> < 0.001), and negatively correlated with perceived stress (<i>p</i> < 0.001). Empathic competence, perceived stress, interpersonal competence, and satisfaction with the participants’ nursing major were identified as factors that influenced the PCC competence (adjusted R<sup>2</sup> = 0.570). <i>Conclusions:</i> To enhance PCC competence in nursing students, empathic competence, interpersonal competence, and satisfaction with the participants’ nursing major need to be improved and perceived stress needs to be reduced.
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