Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation

Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation

Aims: The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous solubility and consequent translation in in vivo performance of Pioglitazone (PE). Material and Methods: Three cyclodextrins: β-cyclodextrin (BCD),...

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Bibliographic Details
Main Authors: Dinesh M Bramhane, Preethi A Kulkarni, Elvis A.F Martis, Raghuvir R. S Pissurlenkar, Evans C Coutinho, Mangal S Nagarsenker
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Anti-diabetic activity
hydroxypropyl-β-cyclodextrin
pioglitazone
β-cyclodextrin
sulfobutylether-7-β-cyclodextrin
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=2;spage=161;epage=169;aulast=Bramhane

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2016;volume=8;issue=2;spage=161;epage=169;aulast=Bramhane

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