Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study
Background/Aims: Appropriate sedation during endoscopy can significantly reduce the discomfort experienced by a patient when the procedure is performed; however, it is associated with several potential risks. Very few reports describe sedation-related adverse events occurring during endoscopy. Our s...
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Yong Chan Lee
2017-12-01
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doaj-10cbb9b5f33d46ef8d35ef5d6dc2e5bb2020-11-24T21:50:10ZengYong Chan LeeThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312017-12-0117418518910.7704/kjhugr.2017.17.4.185kjhugr.2017.17.4.185Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational StudyJihyun Lee0Ki-Nam Shim1Kang Hoon Lee2Ko Eun Lee3Ji Young Chang4Chung Hyun Tae5Chang Mo Moon6Seong-Eun Kim7Hye-Kyung Jung8Sung-Ae Jung9Department of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaDepartment of Internal Medicine, Ewha Medical Research Institute, College of Medicine, Ewha Womans University, Seoul, KoreaBackground/Aims: Appropriate sedation during endoscopy can significantly reduce the discomfort experienced by a patient when the procedure is performed; however, it is associated with several potential risks. Very few reports describe sedation-related adverse events occurring during endoscopy. Our study evaluated the current status of sedation-related adverse events during a diagnostic upper endoscopy. Materials and Methods: We reviewed medical records of 5,564 cases of diagnostic upper endoscopy performed using midazolam for sedation at the Ewha Womans University, Mokdong Hospital, between January 2015 and March 2016. Results: Among the 5,564 cases, sedation-related adverse events were reported in 56 cases (1.0%). Among these 56 patients, 30 patients (53.6.%) were men and 26 patients (46.4%) were women. Mean age of the patients was 63.7±15.4 years. The most common adverse event reported was hypoxia, which was observed in 37 patients (0.7%). Other adverse events included sedation failure (18 patients, 0.3%) and delayed discharge from the recovery room due to delayed recovery of consciousness (one patient, 0.02%). Among patients presenting with hypoxia, 35 patients recovered after administration of intravenous flumazenil and oxygen via nasal prongs. Administration of oxygen alone helped recovery in 2 patients. All patients recovered uneventfully with no mortalities registered. Conclusions: Our study showed that the use of sedative midazolam is relatively safe during an upper endoscopy. The rate of occurrence of adverse events was very low, and no fatal adverse events were observed. However, close observation and continuous monitoring is an essential component of safe sedation during endoscopy.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.185Adverse eventsConscious sedationEndoscopy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jihyun Lee Ki-Nam Shim Kang Hoon Lee Ko Eun Lee Ji Young Chang Chung Hyun Tae Chang Mo Moon Seong-Eun Kim Hye-Kyung Jung Sung-Ae Jung |
spellingShingle |
Jihyun Lee Ki-Nam Shim Kang Hoon Lee Ko Eun Lee Ji Young Chang Chung Hyun Tae Chang Mo Moon Seong-Eun Kim Hye-Kyung Jung Sung-Ae Jung Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study The Korean Journal of Helicobacter and Upper Gastrointestinal Research Adverse events Conscious sedation Endoscopy |
author_facet |
Jihyun Lee Ki-Nam Shim Kang Hoon Lee Ko Eun Lee Ji Young Chang Chung Hyun Tae Chang Mo Moon Seong-Eun Kim Hye-Kyung Jung Sung-Ae Jung |
author_sort |
Jihyun Lee |
title |
Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study |
title_short |
Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study |
title_full |
Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study |
title_fullStr |
Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study |
title_full_unstemmed |
Sedation-related Adverse Events Associated with a Diagnostic Upper Endoscopy: A Single Center-observational Study |
title_sort |
sedation-related adverse events associated with a diagnostic upper endoscopy: a single center-observational study |
publisher |
Yong Chan Lee |
series |
The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
issn |
1738-3331 |
publishDate |
2017-12-01 |
description |
Background/Aims: Appropriate sedation during endoscopy can significantly reduce the discomfort experienced by a patient when the procedure is performed; however, it is associated with several potential risks. Very few reports describe sedation-related adverse events occurring during endoscopy. Our study evaluated the current status of sedation-related adverse events during a diagnostic upper endoscopy. Materials and Methods: We reviewed medical records of 5,564 cases of diagnostic upper endoscopy performed using midazolam for sedation at the Ewha Womans University, Mokdong Hospital, between January 2015 and March 2016. Results: Among the 5,564 cases, sedation-related adverse events were reported in 56 cases (1.0%). Among these 56 patients, 30 patients (53.6.%) were men and 26 patients (46.4%) were women. Mean age of the patients was 63.7±15.4 years. The most common adverse event reported was hypoxia, which was observed in 37 patients (0.7%). Other adverse events included sedation failure (18 patients, 0.3%) and delayed discharge from the recovery room due to delayed recovery of consciousness (one patient, 0.02%). Among patients presenting with hypoxia, 35 patients recovered after administration of intravenous flumazenil and oxygen via nasal prongs. Administration of oxygen alone helped recovery in 2 patients. All patients recovered uneventfully with no mortalities registered. Conclusions: Our study showed that the use of sedative midazolam is relatively safe during an upper endoscopy. The rate of occurrence of adverse events was very low, and no fatal adverse events were observed. However, close observation and continuous monitoring is an essential component of safe sedation during endoscopy. |
topic |
Adverse events Conscious sedation Endoscopy |
url |
http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2017.17.4.185 |
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