PPARγ Cistrome Repression during Activation of Lung Monocyte-Macrophages in Severe COVID-19
Summary: The molecular mechanisms of cytokine storm in patients with severe COVID-19 infections are poorly understood. To uncover these events, we performed transcriptome analyses of lung biopsies from patients with COVID-19, revealing a gene enrichment pattern similar to that of PPARγ-knockout macr...
Main Authors: | Christophe Desterke, Ali G. Turhan, Annelise Bennaceur-Griscelli, Frank Griscelli |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-10-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220308038 |
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