Effect of Spray Drying Conditions on Physical Properties of Panax notoginseng Saponin (PNS) Powder and the Intra-Batch Dissolution Variability of PNS Hydrophilic Matrix Tablet

Effect of Spray Drying Conditions on Physical Properties of Panax notoginseng Saponin (PNS) Powder and the Intra-Batch Dissolution Variability of PNS Hydrophilic Matrix Tablet

Maorui Yang,1 Bing Xu,1,2 Xin Wang,1 Wanting Li,1 Junjie Cao,1 Wenjing Li,1 Yanjiang Qiao1,2 1Department of Chinese Medicine Informatics, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Beijing Key Laboratory of Chinese Medicine Manufacturing Process Control a...

Full description

Bibliographic Details
Main Authors:	Yang M, Xu B, Wang X, Li W, Cao J, Qiao Y
Format:	Article
Language:	English
Published:	Dove Medical Press 2021-03-01
Series:	Drug Design, Development and Therapy
Subjects:	spray drying panax notoginseng saponin hydrophilic matrix tablet dissolution variability quality by design
Online Access:	https://www.dovepress.com/effect-of-spray-drying-conditions-on-physical-properties-of-panax-noto-peer-reviewed-article-DDDT

Similar Items

Dammarane-type Triterpene Saponins from the Flowers of Panax notoginseng
by: Isao Kouno, et al.
Published: (2009-06-01)

New dammarane-type triterpenoid saponins from Panax notoginseng saponins
by: Qian Li, et al.
Published: (2020-09-01)

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
by: Ming Peng, et al.
Published: (2018-03-01)

Suppression of diet-induced hypercholesterolaemia by saponins from Panax notoginseng in rats
by: Jian-Hong Wu, et al.
Published: (2013-07-01)

Anticancer effects of saponin and saponin–phospholipid complex of Panax notoginseng grown in Vietnam
by: Thu Dang Kim, et al.
Published: (2016-09-01)

Eight darmarane-type saponins isolated from the roots of Panax notoginseng
by: Kaunda Joseph Sakah, et al.
Published: (2013-12-01)

5,6-Didehydroginsenosides from the Roots of Panax notoginseng
by: Jian-Bo Wan, et al.
Published: (2010-11-01)

Effects of Panax Notoginseng Saponins on Esterases Responsible for Aspirin Hydrolysis In Vitro
by: Zongxi Sun, et al.
Published: (2018-10-01)

Cardioprotection of Panax Notoginseng saponins against acute myocardial infarction and heart failure through inducing autophagy
by: Dandan Wang, et al.
Published: (2021-04-01)

Panax Notoginseng Saponins Promote Endothelial Progenitor Cell Mobilization and Attenuate Atherosclerotic Lesions in Apolipoprotein E Knockout Mice
by: Ya Liu, et al.
Published: (2013-09-01)

Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice
by: Yong Zhang, et al.
Published: (2019-08-01)

Effects of panax notoginseng saponins on apoptosis, inflammation and oxidative stress in rats with propofol-induced cognitive impairment
by: Yu-Qiang Su, et al.
Published: (2019-05-01)

Panax notoginseng saponins ameliorate cisplatin‐induced mitochondrial injury via the HIF‐1α/mitochondria/ROS pathway
by: Qingqing Li, et al.
Published: (2020-01-01)

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells
by: Zongxi Sun, et al.
Published: (2018-02-01)

Integrated Chemical and Transcriptomic Analysis Reveals the Distribution of Protopanaxadiol- and Protopanaxatriol-Type Saponins in Panax notoginseng
by: Guangfei Wei, et al.
Published: (2018-07-01)

Panax Notoginseng Saponins as a Novel Nature Stabilizer for Poorly Soluble Drug Nanocrystals: A Case Study with Baicalein
by: Yuanbiao Xie, et al.
Published: (2016-08-01)

Panax notoginseng saponins promote endothelial progenitor cell angiogenesis via the Wnt/β-catenin pathway
by: Peiqi Zhu, et al.
Published: (2021-02-01)

Bioactive Protopanaxatriol Type Saponins Isolated from the Roots of Panax Notoginseng (Burk.) F. H. Chen
by: Tao Wang, et al.
Published: (2013-08-01)

Comparative Analysis of Compatibility Influence on Invigorating Blood Circulation for Combined Use of Panax Notoginseng Saponins and Aspirin Using Metabolomics Approach
by: Zongxi Sun, et al.
Published: (2021-04-01)

Antidepressant Effects of Ginsenosides from Panax notoginseng
by: Yang YAO, et al.
Published: (2012-03-01)

DPYSL2 is a novel regulator for neural stem cell differentiation in rats: revealed by Panax notoginseng saponin administration
by: Liu-Lin Xiong, et al.
Published: (2020-04-01)

Anti-inflammatory and Cytotoxic Triterpenes from the Rot Roots of Panax notoginseng
by: Jia-Huan Shang, et al.
Published: (2019-05-01)

Efficacy and Safety of Panax Notoginseng Saponins (Xueshuantong) in Patients With Acute Ischemic Stroke (EXPECT) Trial: Rationale and Design
by: Luda Feng, et al.
Published: (2021-04-01)

Transformation of Panax notoginseng saponins by steaming and Trichoderma longibrachiatum
by: Feng Ge, et al.
Published: (2016-01-01)

Panax Notoginseng Saponins Protect Cardiac Myocytes Against Endoplasmic Reticulum Stress and Associated Apoptosis Through Mediation of Intracellular Calcium Homeostasis
by: Jun Chen, et al.
Published: (2019-09-01)

Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway
by: Qiu-Hong Li, et al.
Published: (2021-01-01)

Personalized bioconversion of Panax notoginseng saponins mediated by gut microbiota between two different diet-pattern healthy subjects
by: Li Wang, et al.
Published: (2021-07-01)

Lowering Nitrogen and Increasing Potassium Application Level Can Improve the Yield and Quality of Panax notoginseng
by: Xiaohong Ou, et al.
Published: (2020-12-01)

Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis
by: Xiuge Tang, et al.
Published: (2020-01-01)

Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis
by: Tao Sun, et al.
Published: (2021-02-01)

Cardioprotective Effect of Stem-Leaf Saponins From Panax notoginseng on Mice With Sleep Derivation by Inhibiting Abnormal Autophagy Through PI3K/Akt/mTOR Pathway
by: Yin Cao, et al.
Published: (2021-09-01)

Preparation, optimization, and in vivo evaluation of an inhaled solution of total saponins of Panax notoginseng and its protective effect against idiopathic pulmonary fibrosis
by: Mengjiao Liu, et al.
Published: (2020-01-01)

Preparation, In Vivo and In Vitro Release of Polyethylene Glycol Monomethyl Ether-Polymandelic Acid Microspheres Loaded <i>Panax Notoginseng Saponins</i>
by: Yi He, et al.
Published: (2019-05-01)

Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats
by: Ming-wei Liu, et al.
Published: (2018-02-01)

Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism
by: Wenting Wang, et al.
Published: (2021-02-01)

Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice
by: Hua Zhong, et al.
Published: (2019-06-01)

20(<i>S</i>)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of <i>Panax notoginseng</i> in ApoE Deficient Mice
by: Conghui Liu, et al.
Published: (2019-10-01)

Diversity, distribution, and antagonistic activities of rhizobacteria of Panax notoginseng
by: Ze-Yan Fan, et al.
Published: (2016-04-01)

Comparison of pharmacokinetics of different oral Panax notoginseng saponins using ultra-high performance liquid mass spectrometry
by: Huichao Wu, et al.
Published: (2021-01-01)

Chemical and bioactive comparison of flowers of Panax ginseng Meyer, Panax quinquefolius L., and Panax notoginseng Burk.
by: Fang Li, et al.
Published: (2017-10-01)