Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins.
Anti-citrullinated protein antibodies (ACPA) have become an integral part of the clinical definition of rheumatoid arthritis, and are hypothesized to be important in the immunopathogenesis of this autoimmune disease. Several citrullinated proteins have been demonstrated to serve as candidate autoant...
Main Authors: | Xiaobo Meng, Peyman Ezzati, Irene Smolik, Charles N Bernstein, Carol Ann Hitchon, Hani S El-Gabalawy |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5082836?pdf=render |
Similar Items
-
Epitope Specificity of Anti-Citrullinated Protein Antibodies
by: Nicole H. Trier, et al.
Published: (2017-03-01) -
Specificity of Anti-Citrullinated Protein Antibodies to Citrullinated α-Enolase Peptides as a Function of Epitope Structure and Composition
by: Ilaria Fanelli, et al.
Published: (2021-07-01) -
Physical Characteristics of a Citrullinated Pro-Filaggrin Epitope Recognized by Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Sera.
by: Nicole Hartwig Trier, et al.
Published: (2016-01-01) -
Investigation of the epitope specificities of antibodies to islet β-cell autoantigens
by: Al-bukhari, Talat Abdullah
Published: (2001) -
The Role of Shared Epitope in Rheumatoid Arthritis Prognosis in Relation to Anti-Citrullinated Protein Antibody Positivity
by: Cui, J., et al.
Published: (2022)