Visual outcome of endogenous endophthalmitis in Thailand

Abstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agent...

Full description

Bibliographic Details
Main Authors: Preeyachan Lourthai, Pitipol Choopong, Dhanach Dhirachaikulpanich, Kunravitch Soraprajum, Warinyupa Pinitpuwadol, Noppakhun Punyayingyong, Yaninsiri Ngathaweesuk, Nattaporn Tesavibul, Sutasinee Boonsopon
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93730-7
id doaj-11209a0e3912472a92b4d31cb5a290d9
record_format Article
spelling doaj-11209a0e3912472a92b4d31cb5a290d92021-07-18T11:27:50ZengNature Publishing GroupScientific Reports2045-23222021-07-011111510.1038/s41598-021-93730-7Visual outcome of endogenous endophthalmitis in ThailandPreeyachan Lourthai0Pitipol Choopong1Dhanach Dhirachaikulpanich2Kunravitch Soraprajum3Warinyupa Pinitpuwadol4Noppakhun Punyayingyong5Yaninsiri Ngathaweesuk6Nattaporn Tesavibul7Sutasinee Boonsopon8Ophthalmology Department, Mettapracharak HospitalDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityOphthalmology Department, Mettapracharak HospitalDepartment of Ophthalmology, Faculty of Medicine, Phramongkutklao Hospital, Phramongkutklao College of MedicineDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityAbstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE.https://doi.org/10.1038/s41598-021-93730-7
collection DOAJ
language English
format Article
sources DOAJ
author Preeyachan Lourthai
Pitipol Choopong
Dhanach Dhirachaikulpanich
Kunravitch Soraprajum
Warinyupa Pinitpuwadol
Noppakhun Punyayingyong
Yaninsiri Ngathaweesuk
Nattaporn Tesavibul
Sutasinee Boonsopon
spellingShingle Preeyachan Lourthai
Pitipol Choopong
Dhanach Dhirachaikulpanich
Kunravitch Soraprajum
Warinyupa Pinitpuwadol
Noppakhun Punyayingyong
Yaninsiri Ngathaweesuk
Nattaporn Tesavibul
Sutasinee Boonsopon
Visual outcome of endogenous endophthalmitis in Thailand
Scientific Reports
author_facet Preeyachan Lourthai
Pitipol Choopong
Dhanach Dhirachaikulpanich
Kunravitch Soraprajum
Warinyupa Pinitpuwadol
Noppakhun Punyayingyong
Yaninsiri Ngathaweesuk
Nattaporn Tesavibul
Sutasinee Boonsopon
author_sort Preeyachan Lourthai
title Visual outcome of endogenous endophthalmitis in Thailand
title_short Visual outcome of endogenous endophthalmitis in Thailand
title_full Visual outcome of endogenous endophthalmitis in Thailand
title_fullStr Visual outcome of endogenous endophthalmitis in Thailand
title_full_unstemmed Visual outcome of endogenous endophthalmitis in Thailand
title_sort visual outcome of endogenous endophthalmitis in thailand
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-07-01
description Abstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE.
url https://doi.org/10.1038/s41598-021-93730-7
work_keys_str_mv AT preeyachanlourthai visualoutcomeofendogenousendophthalmitisinthailand
AT pitipolchoopong visualoutcomeofendogenousendophthalmitisinthailand
AT dhanachdhirachaikulpanich visualoutcomeofendogenousendophthalmitisinthailand
AT kunravitchsoraprajum visualoutcomeofendogenousendophthalmitisinthailand
AT warinyupapinitpuwadol visualoutcomeofendogenousendophthalmitisinthailand
AT noppakhunpunyayingyong visualoutcomeofendogenousendophthalmitisinthailand
AT yaninsiringathaweesuk visualoutcomeofendogenousendophthalmitisinthailand
AT nattaporntesavibul visualoutcomeofendogenousendophthalmitisinthailand
AT sutasineeboonsopon visualoutcomeofendogenousendophthalmitisinthailand
_version_ 1721296084887666688