Visual outcome of endogenous endophthalmitis in Thailand
Abstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agent...
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2021-07-01
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Online Access: | https://doi.org/10.1038/s41598-021-93730-7 |
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doaj-11209a0e3912472a92b4d31cb5a290d92021-07-18T11:27:50ZengNature Publishing GroupScientific Reports2045-23222021-07-011111510.1038/s41598-021-93730-7Visual outcome of endogenous endophthalmitis in ThailandPreeyachan Lourthai0Pitipol Choopong1Dhanach Dhirachaikulpanich2Kunravitch Soraprajum3Warinyupa Pinitpuwadol4Noppakhun Punyayingyong5Yaninsiri Ngathaweesuk6Nattaporn Tesavibul7Sutasinee Boonsopon8Ophthalmology Department, Mettapracharak HospitalDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityOphthalmology Department, Mettapracharak HospitalDepartment of Ophthalmology, Faculty of Medicine, Phramongkutklao Hospital, Phramongkutklao College of MedicineDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityDepartment of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityAbstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE.https://doi.org/10.1038/s41598-021-93730-7 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Preeyachan Lourthai Pitipol Choopong Dhanach Dhirachaikulpanich Kunravitch Soraprajum Warinyupa Pinitpuwadol Noppakhun Punyayingyong Yaninsiri Ngathaweesuk Nattaporn Tesavibul Sutasinee Boonsopon |
spellingShingle |
Preeyachan Lourthai Pitipol Choopong Dhanach Dhirachaikulpanich Kunravitch Soraprajum Warinyupa Pinitpuwadol Noppakhun Punyayingyong Yaninsiri Ngathaweesuk Nattaporn Tesavibul Sutasinee Boonsopon Visual outcome of endogenous endophthalmitis in Thailand Scientific Reports |
author_facet |
Preeyachan Lourthai Pitipol Choopong Dhanach Dhirachaikulpanich Kunravitch Soraprajum Warinyupa Pinitpuwadol Noppakhun Punyayingyong Yaninsiri Ngathaweesuk Nattaporn Tesavibul Sutasinee Boonsopon |
author_sort |
Preeyachan Lourthai |
title |
Visual outcome of endogenous endophthalmitis in Thailand |
title_short |
Visual outcome of endogenous endophthalmitis in Thailand |
title_full |
Visual outcome of endogenous endophthalmitis in Thailand |
title_fullStr |
Visual outcome of endogenous endophthalmitis in Thailand |
title_full_unstemmed |
Visual outcome of endogenous endophthalmitis in Thailand |
title_sort |
visual outcome of endogenous endophthalmitis in thailand |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-07-01 |
description |
Abstract To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE. |
url |
https://doi.org/10.1038/s41598-021-93730-7 |
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