Hydrogen sulfide increases nitric oxide production from endothelial cells by an Akt-dependent mechanism

Hydrogen sulfide (H2S) and nitric oxide (NO) are both gasotransmitters that can elicit synergistic vasodilatory responses in the in the cardiovascular system, but the mechanisms behind this synergy are unclear. In the current study we investigated the molecular mechanisms through which H2S regulates...

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Bibliographic Details
Main Authors: Arturo J Cardounel, David eJulian, Benjamin L Predmore
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Physiology
Subjects:
Akt
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00104/full