Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones

Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.

Bibliographic Details
Main Authors: Katayama Shin-taro, Nishino Hiroshi
Format: Article
Language:English
Published: De Gruyter 2019-12-01
Series:Heterocyclic Communications
Subjects:
Online Access:https://doi.org/10.1515/hc-2019-0022
Description
Summary:Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.
ISSN:2191-0197