Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones

Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.

Bibliographic Details
Main Authors: Katayama Shin-taro, Nishino Hiroshi
Format: Article
Language:English
Published: De Gruyter 2019-12-01
Series:Heterocyclic Communications
Subjects:
Online Access:https://doi.org/10.1515/hc-2019-0022
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spelling doaj-11409697166749d8899082a4160df4ee2021-09-06T19:19:48ZengDe GruyterHeterocyclic Communications2191-01972019-12-0125115716110.1515/hc-2019-0022Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-dionesKatayama Shin-taro0Nishino Hiroshi1Department of Chemistry, Graduate School of Science, Kumamoto University, Kurokami 2-39-1, Chûou-Ku, Kumamoto 860-8555, JapanDepartment of Chemistry, Graduate School of Science, Kumamoto University, Kurokami 2-39-1, Chûou-Ku, Kumamoto 860-8555, JapanSpiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.https://doi.org/10.1515/hc-2019-0022spiro[cyclohexane-1,3’-indoline]-2,2’-dionesoxidative cyclization5-exo cyclizationradicalsheterocycles
collection DOAJ
language English
format Article
sources DOAJ
author Katayama Shin-taro
Nishino Hiroshi
spellingShingle Katayama Shin-taro
Nishino Hiroshi
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
Heterocyclic Communications
spiro[cyclohexane-1,3’-indoline]-2,2’-diones
oxidative cyclization
5-exo cyclization
radicals
heterocycles
author_facet Katayama Shin-taro
Nishino Hiroshi
author_sort Katayama Shin-taro
title Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
title_short Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
title_full Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
title_fullStr Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
title_full_unstemmed Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
title_sort facile synthesis of spiro[cyclohexane-1,3’-indoline]-2,2’-diones
publisher De Gruyter
series Heterocyclic Communications
issn 2191-0197
publishDate 2019-12-01
description Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.
topic spiro[cyclohexane-1,3’-indoline]-2,2’-diones
oxidative cyclization
5-exo cyclization
radicals
heterocycles
url https://doi.org/10.1515/hc-2019-0022
work_keys_str_mv AT katayamashintaro facilesynthesisofspirocyclohexane13indoline22diones
AT nishinohiroshi facilesynthesisofspirocyclohexane13indoline22diones
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