Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones
Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.
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Online Access: | https://doi.org/10.1515/hc-2019-0022 |
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doaj-11409697166749d8899082a4160df4ee2021-09-06T19:19:48ZengDe GruyterHeterocyclic Communications2191-01972019-12-0125115716110.1515/hc-2019-0022Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-dionesKatayama Shin-taro0Nishino Hiroshi1Department of Chemistry, Graduate School of Science, Kumamoto University, Kurokami 2-39-1, Chûou-Ku, Kumamoto 860-8555, JapanDepartment of Chemistry, Graduate School of Science, Kumamoto University, Kurokami 2-39-1, Chûou-Ku, Kumamoto 860-8555, JapanSpiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.https://doi.org/10.1515/hc-2019-0022spiro[cyclohexane-1,3’-indoline]-2,2’-dionesoxidative cyclization5-exo cyclizationradicalsheterocycles |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Katayama Shin-taro Nishino Hiroshi |
spellingShingle |
Katayama Shin-taro Nishino Hiroshi Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones Heterocyclic Communications spiro[cyclohexane-1,3’-indoline]-2,2’-diones oxidative cyclization 5-exo cyclization radicals heterocycles |
author_facet |
Katayama Shin-taro Nishino Hiroshi |
author_sort |
Katayama Shin-taro |
title |
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
title_short |
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
title_full |
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
title_fullStr |
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
title_full_unstemmed |
Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
title_sort |
facile synthesis of spiro[cyclohexane-1,3’-indoline]-2,2’-diones |
publisher |
De Gruyter |
series |
Heterocyclic Communications |
issn |
2191-0197 |
publishDate |
2019-12-01 |
description |
Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products. |
topic |
spiro[cyclohexane-1,3’-indoline]-2,2’-diones oxidative cyclization 5-exo cyclization radicals heterocycles |
url |
https://doi.org/10.1515/hc-2019-0022 |
work_keys_str_mv |
AT katayamashintaro facilesynthesisofspirocyclohexane13indoline22diones AT nishinohiroshi facilesynthesisofspirocyclohexane13indoline22diones |
_version_ |
1717777801369616384 |