Epidemiology of acute decompensated heart failure in India : The AFAR study (Acute failure registry study)

• Main Authors: Sandeep Seth, Suraj Khanal, Sivasubramanian Ramakrishnan, Namit Gupta, Vinay K Bahl
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Journal of the Practice of Cardiovascular Sciences
• Subjects: Acute; decompensated; heart failure; India
• Online Access: http://www.j-pcs.org/article.asp?issn=2395-5414;year=2015;volume=1;issue=1;spage=35;epage=38;aulast=Seth

Objectives: There is a paucity of data on acute decompensated heart failure (ADHF) in Indian patients. We herein report the in-hospital and 6-month outcome of Indian patients admitted with ADHF. Methods: We prospectively enrolled consecutive patients with ADHF due to systolic dysfunction in the acute failure registry and followed them up for at least 6 months. We analyzed the data on death and hospitalization of the first 90 patients on death and hospitalization over 6-months. Results: A total of 90 patients were enrolled with a mean age of 53.5 ± 17. 7 years and the majority were male (63%). The mean left ventricular ejection fraction was 29.2± 11.9%. The in hospital mortality was 30.8%. Postdischarge 6-month major adverse event (re-hospitalization/mortality combined) and mortality rates were 39.5% and 26.3%, respectively. Conclusions: These data from a single referral center provide insights into the current status of acute HF care in India. We report a higher in-hospital and follow-up mortality rates in ADHF patients who present at younger ages than reported in Western literature.