High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.

High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.

Profiling microbial community function from metagenomic sequencing data remains a computationally challenging problem. Mapping millions of DNA reads from such samples to reference protein databases requires long run-times, and short read lengths can result in spurious hits to unrelated proteins (los...

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Bibliographic Details
Main Authors: James Kaminski, Molly K Gibson, Eric A Franzosa, Nicola Segata, Gautam Dantas, Curtis Huttenhower
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004557

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