Antimicrobial activity in vitro of camu-camu (Myrciaria dubia) against oral microorganisms: a systematic review

Objectives. To evaluate the antimicrobial activity of Myrciaria dubia on oral microorganisms. Materials and Methods. A systematic review of the literature following PRISMA guidelines was conducted through searches of studies published between 2008 and 2018 in Pubmed, LILACS, SciELO, ProQuest, EBSCO,...

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Bibliographic Details
Main Authors: Karina Pardo-Aldave, Maria Pareja-Vásquez, Alfredo Guillén, Juan Manuel Ureta-Tapia
Format: Article
Language:Spanish
Published: Instituto Nacional de Salud 2019-12-01
Series:Revista Peruana de Medicina Experimental y Salud Pública
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Online Access:https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4270
Description
Summary:Objectives. To evaluate the antimicrobial activity of Myrciaria dubia on oral microorganisms. Materials and Methods. A systematic review of the literature following PRISMA guidelines was conducted through searches of studies published between 2008 and 2018 in Pubmed, LILACS, SciELO, ProQuest, EBSCO, and Google Scholar. Results. Eleven (11) in vitro studies were gathered; all the studies showed positive antimicrobial activity on gram-positives, mainly by each of the parts of its fruits. However, such activity compared to chlorhexidine in only two studies, and, in another study, it was better than an antibiotic. A high risk of bias was detected in most studies. Phenolic compounds, including polyphenols and acylphloroglucinols, were identified as responsible for its activity. Conclusions. There is evidence of antimicrobial activity in M. dubia. Its study as an antimicrobial against oral microorganisms is still incipient, but there is great potential thanks to the potent phytochemicals it contains. Also, additional quality studies are required: comparing their activity versus oral antiseptics and on microorganisms associated with dental caries and periodontal disease.
ISSN:1726-4634
1726-4642