Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography

Spectral domain coherence tomography (SD OCT) has become an important tool in the management of pediatric retinal diseases. It is a noncontact imaging device that provides detailed assessment of the microanatomy and pathology of the infant retina with a short acquisition time allowing office examina...

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Main Authors: Anand Vinekar, Shwetha Mangalesh, Chaitra Jayadev, Ramiro S. Maldonado, Noel Bauer, Cynthia A. Toth
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/782420
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spelling doaj-1169961eff4d423b947bd56d9157173f2020-11-24T20:47:04ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/782420782420Retinal Imaging of Infants on Spectral Domain Optical Coherence TomographyAnand Vinekar0Shwetha Mangalesh1Chaitra Jayadev2Ramiro S. Maldonado3Noel Bauer4Cynthia A. Toth5Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, IndiaNarayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, IndiaNarayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, IndiaDepartment of Ophthalmology, Duke University, Durham, NC, USADepartment of Ophthalmology, Maastricht University, NetherlandsDepartment of Ophthalmology, Duke University, Durham, NC, USASpectral domain coherence tomography (SD OCT) has become an important tool in the management of pediatric retinal diseases. It is a noncontact imaging device that provides detailed assessment of the microanatomy and pathology of the infant retina with a short acquisition time allowing office examination without the requirement of anesthesia. Our understanding of the development and maturation of the infant fovea has been enhanced by SD OCT allowing an in vivo assessment that correlates with histopathology. This has helped us understand the critical correlation of foveal development with visual potential in the first year of life and beyond. In this review, we summarize the recent literature on the clinical applications of SD OCT in studying the pathoanatomy of the infant macula, its ability to detect subclinical features, and its correlation with disease and vision. Retinopathy of prematurity and macular edema have been discussed in detail. The review also summarizes the current status of SD OCT in other infant retinal conditions, imaging the optic nerve, the choroid, and the retinal nerve fibre in infants and children, and suggests future areas of research.http://dx.doi.org/10.1155/2015/782420
collection DOAJ
language English
format Article
sources DOAJ
author Anand Vinekar
Shwetha Mangalesh
Chaitra Jayadev
Ramiro S. Maldonado
Noel Bauer
Cynthia A. Toth
spellingShingle Anand Vinekar
Shwetha Mangalesh
Chaitra Jayadev
Ramiro S. Maldonado
Noel Bauer
Cynthia A. Toth
Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
BioMed Research International
author_facet Anand Vinekar
Shwetha Mangalesh
Chaitra Jayadev
Ramiro S. Maldonado
Noel Bauer
Cynthia A. Toth
author_sort Anand Vinekar
title Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
title_short Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
title_full Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
title_fullStr Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
title_full_unstemmed Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography
title_sort retinal imaging of infants on spectral domain optical coherence tomography
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Spectral domain coherence tomography (SD OCT) has become an important tool in the management of pediatric retinal diseases. It is a noncontact imaging device that provides detailed assessment of the microanatomy and pathology of the infant retina with a short acquisition time allowing office examination without the requirement of anesthesia. Our understanding of the development and maturation of the infant fovea has been enhanced by SD OCT allowing an in vivo assessment that correlates with histopathology. This has helped us understand the critical correlation of foveal development with visual potential in the first year of life and beyond. In this review, we summarize the recent literature on the clinical applications of SD OCT in studying the pathoanatomy of the infant macula, its ability to detect subclinical features, and its correlation with disease and vision. Retinopathy of prematurity and macular edema have been discussed in detail. The review also summarizes the current status of SD OCT in other infant retinal conditions, imaging the optic nerve, the choroid, and the retinal nerve fibre in infants and children, and suggests future areas of research.
url http://dx.doi.org/10.1155/2015/782420
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