Versatile modeling and optimization of fed batch processes for the production of secreted heterologous proteins with <it>Pichia pastoris</it>

<p>Abstract</p> <p>Background</p> <p>Secretion of heterologous proteins depends both on biomass concentration and on the specific product secretion rate, which in turn is not constant at varying specific growth rates. As fed batch processes usually do not maintain a ste...

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Bibliographic Details
Main Authors: Gasser Brigitte, Kühleitner Manfred, Maurer Michael, Mattanovich Diethard
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/5/1/37