Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis

Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and t...

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Main Authors:	Abel Decmann, Pál Perge, Peter Istvan Turai, Attila Patócs, Peter Igaz
Format:	Article
Language:	English
Published:	MDPI AG 2020-02-01
Series:	Cancers
Subjects:	non-coding rna microrna lncrna adrenocortical cancer biomarker
Online Access:	https://www.mdpi.com/2072-6694/12/2/461

id	doaj-118ae2a0e5ee4f71b791705448ac1e3a
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spelling	doaj-118ae2a0e5ee4f71b791705448ac1e3a2020-11-25T00:15:38ZengMDPI AGCancers2072-66942020-02-0112246110.3390/cancers12020461cancers12020461Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to DiagnosisAbel Decmann0Pál Perge1Peter Istvan Turai2Attila Patócs3Peter Igaz42nd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Szentkirályi Str. 46., H-1088 Budapest, Hungary2nd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Szentkirályi Str. 46., H-1088 Budapest, Hungary2nd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Szentkirályi Str. 46., H-1088 Budapest, HungaryMTA-SE Lendület Hereditary Endocrine Tumors Research Group, H-1089 Budapest, Hungary2nd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Szentkirályi Str. 46., H-1088 Budapest, HungaryNon-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood.https://www.mdpi.com/2072-6694/12/2/461non-coding rnamicrornalncrnaadrenocortical cancerbiomarker
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Abel Decmann Pál Perge Peter Istvan Turai Attila Patócs Peter Igaz
spellingShingle	Abel Decmann Pál Perge Peter Istvan Turai Attila Patócs Peter Igaz Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis Cancers non-coding rna microrna lncrna adrenocortical cancer biomarker
author_facet	Abel Decmann Pál Perge Peter Istvan Turai Attila Patócs Peter Igaz
author_sort	Abel Decmann
title	Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
title_short	Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
title_full	Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
title_fullStr	Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
title_full_unstemmed	Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
title_sort	non-coding rnas in adrenocortical cancer: from pathogenesis to diagnosis
publisher	MDPI AG
series	Cancers
issn	2072-6694
publishDate	2020-02-01
description	Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood.
topic	non-coding rna microrna lncrna adrenocortical cancer biomarker
url	https://www.mdpi.com/2072-6694/12/2/461
work_keys_str_mv	AT abeldecmann noncodingrnasinadrenocorticalcancerfrompathogenesistodiagnosis AT palperge noncodingrnasinadrenocorticalcancerfrompathogenesistodiagnosis AT peteristvanturai noncodingrnasinadrenocorticalcancerfrompathogenesistodiagnosis AT attilapatocs noncodingrnasinadrenocorticalcancerfrompathogenesistodiagnosis AT peterigaz noncodingrnasinadrenocorticalcancerfrompathogenesistodiagnosis
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Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis

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