The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes the RNA-binding protein RBM3 (RNA-binding moti...

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Bibliographic Details
Main Authors: Sophorn Chip, Andrea Zelmer, Omolara O. Ogunshola, Ursula Felderhoff-Mueser, Cordula Nitsch, Christoph Bührer, Sven Wellmann
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Neurobiology of Disease
Subjects:
Brain
Neuron
Apoptosis
Infant
Asphyxia
Hypoxia-ischemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111001276

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