Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers

Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers

The dynamics of cell morphology, in particular membrane blebbing, was studied after induction of apoptosis by etoposide or camptothecin in four human stabilized cell lines (Hep2, Bowes, HT-29 and HL-60). Time lapse videomicroscopy and F-actin staining revealed various dynamic parameters of this proc...

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Format: Article
Language:English
Published: Karolinum Press 2005-01-01
Series:Acta Medica
Subjects:
Apoptosis
Membrane blebbing
Cytoskeleton
F-actin
In vitro
Online Access:https://actamedica.lfhk.cuni.cz/48/1/0029/
id doaj-11a4e53cee2a4304ba375f42a9ca5041
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spelling doaj-11a4e53cee2a4304ba375f42a9ca50412020-11-24T23:17:50ZengKarolinum PressActa Medica1211-42861805-96942005-01-01481293410.14712/18059694.2018.25Membrane Blebbing in Cancer Cells Treated with Various Apoptotic InducersThe dynamics of cell morphology, in particular membrane blebbing, was studied after induction of apoptosis by etoposide or camptothecin in four human stabilized cell lines (Hep2, Bowes, HT-29 and HL-60). Time lapse videomicroscopy and F-actin staining revealed various dynamic parameters of this process including its duration, maximal extent, stages and final endpoints in individual cells. Although generally occurring in predictable patterns, our results indicate a relatively significant variability both in appearance and temporal organization of blebbing not only between different cell lines but also within them.https://actamedica.lfhk.cuni.cz/48/1/0029/ApoptosisMembrane blebbingCytoskeletonF-actinIn vitro
collection DOAJ
language English
format Article
sources DOAJ
title Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
spellingShingle Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
Acta Medica
Apoptosis
Membrane blebbing
Cytoskeleton
F-actin
In vitro
title_short Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
title_full Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
title_fullStr Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
title_full_unstemmed Membrane Blebbing in Cancer Cells Treated with Various Apoptotic Inducers
title_sort membrane blebbing in cancer cells treated with various apoptotic inducers
publisher Karolinum Press
series Acta Medica
issn 1211-4286
1805-9694
publishDate 2005-01-01
description The dynamics of cell morphology, in particular membrane blebbing, was studied after induction of apoptosis by etoposide or camptothecin in four human stabilized cell lines (Hep2, Bowes, HT-29 and HL-60). Time lapse videomicroscopy and F-actin staining revealed various dynamic parameters of this process including its duration, maximal extent, stages and final endpoints in individual cells. Although generally occurring in predictable patterns, our results indicate a relatively significant variability both in appearance and temporal organization of blebbing not only between different cell lines but also within them.
topic Apoptosis
Membrane blebbing
Cytoskeleton
F-actin
In vitro
url https://actamedica.lfhk.cuni.cz/48/1/0029/
_version_ 1725583104510263296

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