Radiation impairs perineural invasion by modulating the nerve microenvironment.
Perineural invasion (PNI) by cancer cells is an ominous clinical event that is associated with increased local recurrence and poor prognosis. Although radiation therapy (RT) may be delivered along the course of an invaded nerve, the mechanisms through which radiation may potentially control PNI rema...
Main Authors: | Richard L Bakst, Nancy Lee, Shuangba He, Natalya Chernichenko, Chun-Hao Chen, Gary Linkov, H Carl Le, Jason Koutcher, Efsevia Vakiani, Richard J Wong |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3386941?pdf=render |
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