Diagnostic performance of PET/CT in primary malignant bone tumors
Abstract Background Nowadays, PET/CT plays a substantial role in the diagnosis of different types of tumor by its ability to provide combined functional and anatomic imaging in the same session. The purpose of this study is to evaluate the added value of PET/CT in staging and re-staging of primary m...
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doaj-11d03d305c9c499a81afdb0d9df814de2021-10-03T11:38:51ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622021-09-0152111310.1186/s43055-021-00618-7Diagnostic performance of PET/CT in primary malignant bone tumorsAhmed Eid Fahim Abdella0Khaled Ismail Elshafey1Mohammed Fouad Sherif2Hanan Ahmad Nagy3Nasser Institute for Research and TreatmentFaculty of Medicine, Tanta UniversityFaculty of Medicine, Tanta UniversityFaculty of Medicine, Tanta UniversityAbstract Background Nowadays, PET/CT plays a substantial role in the diagnosis of different types of tumor by its ability to provide combined functional and anatomic imaging in the same session. The purpose of this study is to evaluate the added value of PET/CT in staging and re-staging of primary malignant bone tumors. Results Out of the studied 40 patients, 7 patients were referred for primary staging of different types of histologically proven primary malignant bone tumors, their FDG-PET/CT studies yielded additional diagnostic information in 28.6% of them. Thirty three patients were referred either for assessment of treatment response or for follow-up to detect any viable lesions; FDG-PET/CT was more sensitive and specific than CT in follow-up and assessment of treatment response with PET/CT sensitivity 94.4%, specificity 86.7%, and total accuracy 90.9% and CT sensitivity 88.2%, specificity 81.2%, and total accuracy 84.8%. Conclusions PET/CT was an accurate imaging modality in evaluation of primary malignant bone tumors regarding tumor staging, assessment of therapeutic response and detection of metastatic disease as compared to CT.https://doi.org/10.1186/s43055-021-00618-7Positron emission tomography/computed tomography (PET-CT)Malignant bone tumorsFDGPrimary satgingSUVmax |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ahmed Eid Fahim Abdella Khaled Ismail Elshafey Mohammed Fouad Sherif Hanan Ahmad Nagy |
spellingShingle |
Ahmed Eid Fahim Abdella Khaled Ismail Elshafey Mohammed Fouad Sherif Hanan Ahmad Nagy Diagnostic performance of PET/CT in primary malignant bone tumors The Egyptian Journal of Radiology and Nuclear Medicine Positron emission tomography/computed tomography (PET-CT) Malignant bone tumors FDG Primary satging SUVmax |
author_facet |
Ahmed Eid Fahim Abdella Khaled Ismail Elshafey Mohammed Fouad Sherif Hanan Ahmad Nagy |
author_sort |
Ahmed Eid Fahim Abdella |
title |
Diagnostic performance of PET/CT in primary malignant bone tumors |
title_short |
Diagnostic performance of PET/CT in primary malignant bone tumors |
title_full |
Diagnostic performance of PET/CT in primary malignant bone tumors |
title_fullStr |
Diagnostic performance of PET/CT in primary malignant bone tumors |
title_full_unstemmed |
Diagnostic performance of PET/CT in primary malignant bone tumors |
title_sort |
diagnostic performance of pet/ct in primary malignant bone tumors |
publisher |
SpringerOpen |
series |
The Egyptian Journal of Radiology and Nuclear Medicine |
issn |
2090-4762 |
publishDate |
2021-09-01 |
description |
Abstract Background Nowadays, PET/CT plays a substantial role in the diagnosis of different types of tumor by its ability to provide combined functional and anatomic imaging in the same session. The purpose of this study is to evaluate the added value of PET/CT in staging and re-staging of primary malignant bone tumors. Results Out of the studied 40 patients, 7 patients were referred for primary staging of different types of histologically proven primary malignant bone tumors, their FDG-PET/CT studies yielded additional diagnostic information in 28.6% of them. Thirty three patients were referred either for assessment of treatment response or for follow-up to detect any viable lesions; FDG-PET/CT was more sensitive and specific than CT in follow-up and assessment of treatment response with PET/CT sensitivity 94.4%, specificity 86.7%, and total accuracy 90.9% and CT sensitivity 88.2%, specificity 81.2%, and total accuracy 84.8%. Conclusions PET/CT was an accurate imaging modality in evaluation of primary malignant bone tumors regarding tumor staging, assessment of therapeutic response and detection of metastatic disease as compared to CT. |
topic |
Positron emission tomography/computed tomography (PET-CT) Malignant bone tumors FDG Primary satging SUVmax |
url |
https://doi.org/10.1186/s43055-021-00618-7 |
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