Tailoring Midazolam-Loaded Chitosan Nanoparticulate Formulation for Enhanced Brain Delivery via Intranasal Route

Tailoring Midazolam-Loaded Chitosan Nanoparticulate Formulation for Enhanced Brain Delivery via Intranasal Route

In the present study, midazolam (MDZ)-loaded chitosan nanoparticle formulation was investigated for enhanced transport to the brain through the intranasal (IN) route. These days, IN MDZ is very much in demand for treating life-threatening seizure emergencies; therefore, its nanoparticle formulation...

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Bibliographic Details
Main Authors: Nikesh Shrestha, Saba Khan, Yub Raj Neupane, Shweta Dang, Shadab Md, Usama A. Fahmy, Sabna Kotta, Nabil A. Alhakamy, Sanjula Baboota, Javed Ali
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Polymers
Subjects:
midazolam
status epilepticus
chitosan
nanoparticles
ionic gelation method
intranasal route
Online Access:https://www.mdpi.com/2073-4360/12/11/2589

Internet

https://www.mdpi.com/2073-4360/12/11/2589

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