Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019

ObjectiveWe aimed to investigate the consumption and lack of access to medicines in the adult population of Manaus, Amazonas.MethodsA population-based study was conducted in Manaus in 2019. Individuals aged ≥18 years were selected by probabilistic sampling performed in three stages. Study outcomes i...

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Main Authors: Gustavo Magno Baldin Tiguman, Marcus Tolentino Silva, Taís Freire Galvão
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.586559/full
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spelling doaj-11e8f3ee55e84a02865a0a5294338e692020-11-25T03:53:41ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122020-10-011110.3389/fphar.2020.586559586559Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019Gustavo Magno Baldin Tiguman0Marcus Tolentino Silva1Taís Freire Galvão2Faculty of Pharmaceutical Sciences, State University of Campinas, Campinas, BrazilPost-Graduate Program of Pharmaceutical Sciences, University of Sorocaba, Sorocaba, BrazilFaculty of Pharmaceutical Sciences, State University of Campinas, Campinas, BrazilObjectiveWe aimed to investigate the consumption and lack of access to medicines in the adult population of Manaus, Amazonas.MethodsA population-based study was conducted in Manaus in 2019. Individuals aged ≥18 years were selected by probabilistic sampling performed in three stages. Study outcomes included the consumption of medicines in the previous fortnight and the lack of access to treatments in those who used any medicine. We calculated the prevalence ratios (PR) for the outcomes with 95% confidence intervals (CI) by Poisson regression with robust variance, considering the complex sampling design.ResultsOut of the 2,321 participants, 53.2% (95%CI 50.7-55.7%) consumed medicines, of which 14.4% (95% CI 11.9–16.8%) could not obtain appropriate treatments. Analgesics were the most used medicines (557/2,702; 21.4%), whereas antibiotics were the most inaccessible treatments (18/228; 7.9%). Lack of financial resources was the main reason for not accessing treatments (104/228; 45.6%). Consumption was significantly associated with older age (≥60 years: PR = 1.27; 95%CI 1.09–1.49), lower social class (D/E: PR = 0.84; 95%CI 0.72–0.99), lower educational level (p = 0.039), poor health status (PR = 1.30; 95%CI 1.11–1.52), use of health care services (PR = 1.37; 95%CI 1.26–1.49), and chronic diseases (PR = 1.36; 95%CI 1.22–1.52). Lack of access was higher in people with poor health status (PR = 2.46; 95%CI 1.50–4.04) and chronic diseases (PR = 1.84; 95%CI 1.16–2.92).ConclusionHalf of Manaus’ population used medicines, which was higher in socially privileged and sicker individuals. Among those, 14 in every 100 could not access drug therapies, which was more frequent in people with poor health and with chronic diseases.https://www.frontiersin.org/article/10.3389/fphar.2020.586559/fulldrug utilizationAccess to Essential Medicines and Health Technologieshealth services accessibilitycross-sectional studiesBrazil
collection DOAJ
language English
format Article
sources DOAJ
author Gustavo Magno Baldin Tiguman
Marcus Tolentino Silva
Taís Freire Galvão
spellingShingle Gustavo Magno Baldin Tiguman
Marcus Tolentino Silva
Taís Freire Galvão
Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
Frontiers in Pharmacology
drug utilization
Access to Essential Medicines and Health Technologies
health services accessibility
cross-sectional studies
Brazil
author_facet Gustavo Magno Baldin Tiguman
Marcus Tolentino Silva
Taís Freire Galvão
author_sort Gustavo Magno Baldin Tiguman
title Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
title_short Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
title_full Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
title_fullStr Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
title_full_unstemmed Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019
title_sort consumption and lack of access to medicines and associated factors in the brazilian amazon: a cross-sectional study, 2019
publisher Frontiers Media S.A.
series Frontiers in Pharmacology
issn 1663-9812
publishDate 2020-10-01
description ObjectiveWe aimed to investigate the consumption and lack of access to medicines in the adult population of Manaus, Amazonas.MethodsA population-based study was conducted in Manaus in 2019. Individuals aged ≥18 years were selected by probabilistic sampling performed in three stages. Study outcomes included the consumption of medicines in the previous fortnight and the lack of access to treatments in those who used any medicine. We calculated the prevalence ratios (PR) for the outcomes with 95% confidence intervals (CI) by Poisson regression with robust variance, considering the complex sampling design.ResultsOut of the 2,321 participants, 53.2% (95%CI 50.7-55.7%) consumed medicines, of which 14.4% (95% CI 11.9–16.8%) could not obtain appropriate treatments. Analgesics were the most used medicines (557/2,702; 21.4%), whereas antibiotics were the most inaccessible treatments (18/228; 7.9%). Lack of financial resources was the main reason for not accessing treatments (104/228; 45.6%). Consumption was significantly associated with older age (≥60 years: PR = 1.27; 95%CI 1.09–1.49), lower social class (D/E: PR = 0.84; 95%CI 0.72–0.99), lower educational level (p = 0.039), poor health status (PR = 1.30; 95%CI 1.11–1.52), use of health care services (PR = 1.37; 95%CI 1.26–1.49), and chronic diseases (PR = 1.36; 95%CI 1.22–1.52). Lack of access was higher in people with poor health status (PR = 2.46; 95%CI 1.50–4.04) and chronic diseases (PR = 1.84; 95%CI 1.16–2.92).ConclusionHalf of Manaus’ population used medicines, which was higher in socially privileged and sicker individuals. Among those, 14 in every 100 could not access drug therapies, which was more frequent in people with poor health and with chronic diseases.
topic drug utilization
Access to Essential Medicines and Health Technologies
health services accessibility
cross-sectional studies
Brazil
url https://www.frontiersin.org/article/10.3389/fphar.2020.586559/full
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