Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study
Background: Work may contribute significantly to daily physical activity (PA) and sedentary behavior (SB). Physical inactivity and SB at work might be two major risk factors for premature morbidity. Therefore, the aim of this research was to describe self-reported past PA and SB at work and during l...
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Frontiers Media S.A.
2019-03-01
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Online Access: | https://www.frontiersin.org/article/10.3389/fpubh.2019.00051/full |
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record_format |
Article |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
David Hupin David Hupin Jérémy Raffin Jérémy Raffin Nathalie Barth Mathieu Berger Martin Garet Kevin Stampone Sébastien Celle Sébastien Celle Vincent Pichot Vincent Pichot Bienvenu Bongue Bienvenu Bongue Bienvenu Bongue Jean-Claude Barthelemy Jean-Claude Barthelemy Jean-Claude Barthelemy Frédéric Roche Frédéric Roche |
spellingShingle |
David Hupin David Hupin Jérémy Raffin Jérémy Raffin Nathalie Barth Mathieu Berger Martin Garet Kevin Stampone Sébastien Celle Sébastien Celle Vincent Pichot Vincent Pichot Bienvenu Bongue Bienvenu Bongue Bienvenu Bongue Jean-Claude Barthelemy Jean-Claude Barthelemy Jean-Claude Barthelemy Frédéric Roche Frédéric Roche Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study Frontiers in Public Health physical activity sedentary behavior work prevention health cardiovascular event |
author_facet |
David Hupin David Hupin Jérémy Raffin Jérémy Raffin Nathalie Barth Mathieu Berger Martin Garet Kevin Stampone Sébastien Celle Sébastien Celle Vincent Pichot Vincent Pichot Bienvenu Bongue Bienvenu Bongue Bienvenu Bongue Jean-Claude Barthelemy Jean-Claude Barthelemy Jean-Claude Barthelemy Frédéric Roche Frédéric Roche |
author_sort |
David Hupin |
title |
Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study |
title_short |
Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study |
title_full |
Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study |
title_fullStr |
Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study |
title_full_unstemmed |
Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort Study |
title_sort |
even a previous light-active physical activity at work still reduces late myocardial infarction and stroke in retired adults aged>65 years by 32%: the proof cohort study |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Public Health |
issn |
2296-2565 |
publishDate |
2019-03-01 |
description |
Background: Work may contribute significantly to daily physical activity (PA) and sedentary behavior (SB). Physical inactivity and SB at work might be two major risk factors for premature morbidity. Therefore, the aim of this research was to describe self-reported past PA and SB at work and during leisure time within the PROOF cohort subjects, and to determine consequences of PA and SB on late health of these now retired workers.Material and Methods: The PROOF cohort study was used to prospectively allow assessment of the predictive value of PA and SB at work and during leisure time among a healthy retired French population, with regard to cardiovascular and cerebrovascular events. PA (MET-h/week) and SB (h/d) were assessed using the Population Physical Activity Questionnaire (POPAQ) and the modified Global Physical Activity Questionnaire (GPAQ). Odds ratios (ORs with 95% CIs) for cardiovascular and cerebrovascular events were associated with each level of PA at work: light (<3 METs), moderate (3–5.9 METs), vigorous (≥6 METs) and were compared to SB at work.Results: Out of the 1011 65-year-old subjects initially included, the 15-year follow-up has been currently completed for 688 (68%) subjects; 89 deaths (all-cause mortality, 9%) and 91 fatal and non-fatal cardiovascular and cerebrovascular events (9%), were reported. An active work (light, moderate, or vigorous intensity) was associated with a 21% reduced risk of cardiovascular (myocardial infarction) and cerebrovascular events (stroke) (OR = 0.79, 95% CI: 0.32–0.91, p < 0.02) compared to sedentary work. This relationship was already significant for light intensity work (32%; i.e., OR = 0.68, 95% CI: 0.31–0.87, p < 0.02).Conclusion: There is strong causal evidence linking PA and SB at work with late cardiovascular and cerebrovascular disease. All in all, the risk for onset of myocardial infarction and stroke was lower among those who had a previous active work compared to those with previous sedentary work. Even previous light active work produced substantial health benefits.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT00759304. |
topic |
physical activity sedentary behavior work prevention health cardiovascular event |
url |
https://www.frontiersin.org/article/10.3389/fpubh.2019.00051/full |
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doaj-11ede890360a4a818099a62a4d2697ac2020-11-25T00:07:57ZengFrontiers Media S.A.Frontiers in Public Health2296-25652019-03-01710.3389/fpubh.2019.00051401532Even a Previous Light-Active Physical Activity at Work Still Reduces Late Myocardial Infarction and Stroke in Retired Adults Aged>65 Years by 32%: The PROOF Cohort StudyDavid Hupin0David Hupin1Jérémy Raffin2Jérémy Raffin3Nathalie Barth4Mathieu Berger5Martin Garet6Kevin Stampone7Sébastien Celle8Sébastien Celle9Vincent Pichot10Vincent Pichot11Bienvenu Bongue12Bienvenu Bongue13Bienvenu Bongue14Jean-Claude Barthelemy15Jean-Claude Barthelemy16Jean-Claude Barthelemy17Frédéric Roche18Frédéric Roche19UJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceDepartment of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceLoire-Haute Loire French Mutuality, SSAM, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceFaculty of Medicine, UJM-Saint-Etienne, Univ. Lyon, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceDepartment of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceDepartment of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceUJM-Saint-Etienne, Chaire Santé des Ainés, Univ. Lyon, Saint-Etienne, FranceSupport and Education Technic Centre of Health Examination Centres (CETAF), Saint-Etienne, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceDepartment of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, Saint-Etienne, FranceFrench Federation of Voluntary Gymnastics (FFEPGV), Montreuil, FranceUJM-Saint-Etienne Autonomic Nervous System Research Laboratory, EA 4607 SNA-EPIS, Univ. Lyon, Saint-Etienne, FranceDepartment of Clinical and Exercise Physiology, University Hospital of Saint-Etienne, Saint-Etienne, FranceBackground: Work may contribute significantly to daily physical activity (PA) and sedentary behavior (SB). Physical inactivity and SB at work might be two major risk factors for premature morbidity. Therefore, the aim of this research was to describe self-reported past PA and SB at work and during leisure time within the PROOF cohort subjects, and to determine consequences of PA and SB on late health of these now retired workers.Material and Methods: The PROOF cohort study was used to prospectively allow assessment of the predictive value of PA and SB at work and during leisure time among a healthy retired French population, with regard to cardiovascular and cerebrovascular events. PA (MET-h/week) and SB (h/d) were assessed using the Population Physical Activity Questionnaire (POPAQ) and the modified Global Physical Activity Questionnaire (GPAQ). Odds ratios (ORs with 95% CIs) for cardiovascular and cerebrovascular events were associated with each level of PA at work: light (<3 METs), moderate (3–5.9 METs), vigorous (≥6 METs) and were compared to SB at work.Results: Out of the 1011 65-year-old subjects initially included, the 15-year follow-up has been currently completed for 688 (68%) subjects; 89 deaths (all-cause mortality, 9%) and 91 fatal and non-fatal cardiovascular and cerebrovascular events (9%), were reported. An active work (light, moderate, or vigorous intensity) was associated with a 21% reduced risk of cardiovascular (myocardial infarction) and cerebrovascular events (stroke) (OR = 0.79, 95% CI: 0.32–0.91, p < 0.02) compared to sedentary work. This relationship was already significant for light intensity work (32%; i.e., OR = 0.68, 95% CI: 0.31–0.87, p < 0.02).Conclusion: There is strong causal evidence linking PA and SB at work with late cardiovascular and cerebrovascular disease. All in all, the risk for onset of myocardial infarction and stroke was lower among those who had a previous active work compared to those with previous sedentary work. Even previous light active work produced substantial health benefits.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT00759304.https://www.frontiersin.org/article/10.3389/fpubh.2019.00051/fullphysical activitysedentary behaviorworkpreventionhealthcardiovascular event |