The Prevalence of Antimicrobial Resistance and Serotypes of Streptococcus pneumoniae in the Kingdom of Bahrain
Streptococcus pneumoniae (S. pneumoniae), also known as pneumococcus, is found in the upper respiratory tract of 5-70% of healthy people. It causes otitis media, pneumonia and invasive pneumococcal diseases (IPD). The group with the highest risk for pneumococcal diseases are children, elderly peo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Journal of Pure and Applied Microbiology
2020-03-01
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| Series: | Journal of Pure and Applied Microbiology |
| Subjects: | |
| Online Access: | https://microbiologyjournal.org/the-prevalence-of-antimicrobial-resistance-and-serotypes-of-streptococcus-pneumoniae-in-the-kingdom-of-bahrain/ |
| Summary: | Streptococcus pneumoniae (S. pneumoniae), also known as pneumococcus, is found in the upper
respiratory tract of 5-70% of healthy people. It causes otitis media, pneumonia and invasive
pneumococcal diseases (IPD). The group with the highest risk for pneumococcal diseases are children,
elderly people and people with chronic systemic illnesses. The identification of these serotypes is
crucial to monitor the prevalent serotypes, to track resistance patterns, and to evaluate the efficacy
of treatment and vaccination. Our aim was to determine antibiotic resistance in S. pneumoniae,
identify the most common serotypes, determine the association between highly resistant strains and
most common serotypes, and select an effective vaccine against the predominant serotypes in the
Kingdom of Bahrain. One hundred isolates were included in the study. Antimicrobial susceptibility was
determined by agar dilution and serotypes were determined by the Quellung reaction. Antimicrobial
resistance rates were highest for penicillin in children ≤ 5 years old (34%) and elderly patients (29%).
For the serotypes distribution of S. pneumoniae, the predominant serotypes were 19, 6, 23, 3 and 14
in the different age groups. The predominant serotypes that showed resistance to three antimicrobial
agents were 19, 6, 23 and 14. The increasing pneumococcal resistance to penicillin, erythromycin, and
tetracycline indicates the need for preventive measures, antibiotics use monitoring and stewarding.
In light of the expanding prevalence of S. pneumoniae resistant to multiple antimicrobial agents, the
need for an effective pneumococcal vaccine has become very important. |
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| ISSN: | 0973-7510 2581-690X |